Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs
India currently has around 77 million adults living with diabetes. Considering the growing impact of diabetes-related complications, we aimed to compare the real-world prescribing patterns of sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors and traditional antidiabetics....
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Light House Polyclinic Mangalore
2025-04-01
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| Series: | Online Journal of Health & Allied Sciences |
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| Online Access: | https://www.ojhas.org/issue93/2025-1-5.html |
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| author | Vini Pavithran Pandiyan Balachandran Chadappully Ismail Sajeeth Athiappan Hariharan |
| author_facet | Vini Pavithran Pandiyan Balachandran Chadappully Ismail Sajeeth Athiappan Hariharan |
| author_sort | Vini Pavithran |
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| description | India currently has around 77 million adults living with diabetes. Considering the growing impact of diabetes-related complications, we aimed to compare the real-world prescribing patterns of sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors and traditional antidiabetics. Using a cross-sectional study design, the prescribing pattern and factors influencing the utilisation of the antidiabetic drugs, categorised by the HbA1c status, were assessed using the chi-square test. Of 260 eligible adults with mean [SD] age, 63.7[12.4] years; 54.7% of male participants initiated treatment with sodium-glucose cotransporter-2 inhibitors (n=27) or a dipeptidyl peptidase-4 inhibitors (n=31). The use of newer antidiabetic agents has steadily increased, with a slightly higher initiation rate in those over 65 years (21.5%). No significant difference was observed based on age (p = 0.182) or gender (p = 0.9548). Prescriber speciality had a significant impact (p = 0.00038). Cardiologists showed the highest shift towards newer drugs (36.5%). Prescriptions of newer antidiabetics have shown an upward trend over time, indicating a shift in prescribing practices. However, this increase was limited. Further efforts are necessary to identify and address the barriers to underutilisation of these drugs. |
| format | Article |
| id | doaj-art-bef719303b554db09b7317e88c1efeba |
| institution | OA Journals |
| issn | 0972-5997 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Light House Polyclinic Mangalore |
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| series | Online Journal of Health & Allied Sciences |
| spelling | doaj-art-bef719303b554db09b7317e88c1efeba2025-08-20T02:26:51ZengLight House Polyclinic MangaloreOnline Journal of Health & Allied Sciences0972-59972025-04-01241Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic DrugsVini Pavithran0Pandiyan Balachandran1Chadappully Ismail Sajeeth2Athiappan Hariharan3Research Scholar, Department of Pharmacy, Annamalai University, Annamalai Nagar, Tamil Nadu, India - 608002Assistant Professor, Department of Pharmacy, Annamalai University, Annamalai Nagar, Tamil Nadu, India - 608002Professor and HOD, Department of Pharmacy, Grace college of Pharmacy, Palakkad, Kerala, India - 678004Assistant Professor, Department of General Medicine, Karuna Medical College and Hospital, Palakkad, Kerala, India - 678103India currently has around 77 million adults living with diabetes. Considering the growing impact of diabetes-related complications, we aimed to compare the real-world prescribing patterns of sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors and traditional antidiabetics. Using a cross-sectional study design, the prescribing pattern and factors influencing the utilisation of the antidiabetic drugs, categorised by the HbA1c status, were assessed using the chi-square test. Of 260 eligible adults with mean [SD] age, 63.7[12.4] years; 54.7% of male participants initiated treatment with sodium-glucose cotransporter-2 inhibitors (n=27) or a dipeptidyl peptidase-4 inhibitors (n=31). The use of newer antidiabetic agents has steadily increased, with a slightly higher initiation rate in those over 65 years (21.5%). No significant difference was observed based on age (p = 0.182) or gender (p = 0.9548). Prescriber speciality had a significant impact (p = 0.00038). Cardiologists showed the highest shift towards newer drugs (36.5%). Prescriptions of newer antidiabetics have shown an upward trend over time, indicating a shift in prescribing practices. However, this increase was limited. Further efforts are necessary to identify and address the barriers to underutilisation of these drugs.https://www.ojhas.org/issue93/2025-1-5.htmldipeptidyl peptidase inhibitorshba1cprescribing patternsodium glucose cotransporter 2 inhibitorstype 2 diabetes mellitus |
| spellingShingle | Vini Pavithran Pandiyan Balachandran Chadappully Ismail Sajeeth Athiappan Hariharan Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs Online Journal of Health & Allied Sciences dipeptidyl peptidase inhibitors hba1c prescribing pattern sodium glucose cotransporter 2 inhibitors type 2 diabetes mellitus |
| title | Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs |
| title_full | Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs |
| title_fullStr | Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs |
| title_full_unstemmed | Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs |
| title_short | Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs |
| title_sort | analysing the shift in prescribing patterns sodium glucose co transporter 2 inhibitors dipeptidyl peptidase 4 inhibitors and traditional antidiabetic drugs |
| topic | dipeptidyl peptidase inhibitors hba1c prescribing pattern sodium glucose cotransporter 2 inhibitors type 2 diabetes mellitus |
| url | https://www.ojhas.org/issue93/2025-1-5.html |
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