Advancing the development of TRIP13 inhibitors: A high-throughput screening approach

TRIP13, a promising target for cancer therapy, has been identified as a key regulator of the mitotic checkpoint. Overexpression of TRIP13 is associated with poor clinical outcomes in various cancers. Inhibition of TRIP13 has the potential to address therapeutic challenges in cancer, particularly in...

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Bibliographic Details
Main Authors: Rae M. Sammons, Soma Ghosh, Lacin Yapindi, Eun Jeong Cho, Faye M. Johnson, Kevin N. Dalby
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:SLAS Discovery
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Online Access:http://www.sciencedirect.com/science/article/pii/S2472555225000267
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