Advancing the development of TRIP13 inhibitors: A high-throughput screening approach
TRIP13, a promising target for cancer therapy, has been identified as a key regulator of the mitotic checkpoint. Overexpression of TRIP13 is associated with poor clinical outcomes in various cancers. Inhibition of TRIP13 has the potential to address therapeutic challenges in cancer, particularly in...
Saved in:
| Main Authors: | Rae M. Sammons, Soma Ghosh, Lacin Yapindi, Eun Jeong Cho, Faye M. Johnson, Kevin N. Dalby |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | SLAS Discovery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2472555225000267 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Exosome-transmitted HSPA9 facilitates bortezomib resistance by targeting TRIP13/USP1 signaling in multiple myeloma
by: Min Shi, et al.
Published: (2025-03-01) -
Targeting Thyroid Hormone Receptor Interacting Protein (TRIP13) for Cancer Therapy: A Promising Approach
by: Surya P. Singh, et al.
Published: (2025-01-01) -
Exploring perceived changes in the frequency of private trips and local trips after telework adoption in France
by: Anne Aguiléra, et al.
Published: (2025-05-01) -
A homozygous TRIP13 pathogenic variant associated with familiar oocyte arrest and prematurely condensed sperm chromosomes
by: Michal Schweiger, et al.
Published: (2025-07-01) -
Modeling The Generation And Attractiveness Of Passenger Demand Trips On The Madiun-Slahung Railway Reactivation Line
by: Arinda Leliana, et al.
Published: (2023-04-01)