The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations
Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preco...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Houston Methodist DeBakey Heart & Vascular Center
2024-03-01
|
| Series: | Methodist DeBakey Cardiovascular Journal |
| Subjects: | |
| Online Access: | https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1371 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849469359028699136 |
|---|---|
| author | Valeria E. Duarte Jessica N. Richardson Michael N. Singh |
| author_facet | Valeria E. Duarte Jessica N. Richardson Michael N. Singh |
| author_sort | Valeria E. Duarte |
| collection | DOAJ |
| description | Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preconception counseling is vital considering the hereditary nature of TAD and potential pregnancy-related complications. Genetic testing and imaging surveillance aid in risk assessment. Medical management, including beta-blockade and strict blood pressure control, is essential throughout pregnancy. Surgical interventions may be necessary in certain cases. A multidisciplinary approach involving cardiologists, obstetricians, cardiac surgeons, anesthesiologists, and other specialists with expertise in cardio-obstetrics is essential for optimal outcomes. Patient education and shared decision-making play vital roles in navigating the complexities of TAD in pregnancy and improving maternal and neonatal outcomes. |
| format | Article |
| id | doaj-art-bef67205322c405f938d625d25bea45f |
| institution | Kabale University |
| issn | 1947-6108 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Houston Methodist DeBakey Heart & Vascular Center |
| record_format | Article |
| series | Methodist DeBakey Cardiovascular Journal |
| spelling | doaj-art-bef67205322c405f938d625d25bea45f2025-08-20T03:25:30ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082024-03-01202515810.14797/mdcvj.13711348The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management ConsiderationsValeria E. Duarte0https://orcid.org/0000-0001-6616-5412Jessica N. Richardson1https://orcid.org/0009-0006-9960-1261Michael N. Singh2https://orcid.org/0000-0002-8667-9872Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas; Boston Children’s Hospital, Harvard Medical School, Boston, MassachusettsHouston Methodist DeBakey Heart & Vascular Center, Houston, TexasBoston Children’s Hospital, Harvard Medical School, Boston, Massachusetts; Brigham and Women’s Hospital, Harvard Medical School, Boston, MassachusettsThoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preconception counseling is vital considering the hereditary nature of TAD and potential pregnancy-related complications. Genetic testing and imaging surveillance aid in risk assessment. Medical management, including beta-blockade and strict blood pressure control, is essential throughout pregnancy. Surgical interventions may be necessary in certain cases. A multidisciplinary approach involving cardiologists, obstetricians, cardiac surgeons, anesthesiologists, and other specialists with expertise in cardio-obstetrics is essential for optimal outcomes. Patient education and shared decision-making play vital roles in navigating the complexities of TAD in pregnancy and improving maternal and neonatal outcomes.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1371pregnancyaortopathymarfancardiovascular genetics |
| spellingShingle | Valeria E. Duarte Jessica N. Richardson Michael N. Singh The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations Methodist DeBakey Cardiovascular Journal pregnancy aortopathy marfan cardiovascular genetics |
| title | The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations |
| title_full | The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations |
| title_fullStr | The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations |
| title_full_unstemmed | The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations |
| title_short | The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations |
| title_sort | impact of pregnancy in patients with thoracic aortic disease epidemiology risk assessment and management considerations |
| topic | pregnancy aortopathy marfan cardiovascular genetics |
| url | https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1371 |
| work_keys_str_mv | AT valeriaeduarte theimpactofpregnancyinpatientswiththoracicaorticdiseaseepidemiologyriskassessmentandmanagementconsiderations AT jessicanrichardson theimpactofpregnancyinpatientswiththoracicaorticdiseaseepidemiologyriskassessmentandmanagementconsiderations AT michaelnsingh theimpactofpregnancyinpatientswiththoracicaorticdiseaseepidemiologyriskassessmentandmanagementconsiderations AT valeriaeduarte impactofpregnancyinpatientswiththoracicaorticdiseaseepidemiologyriskassessmentandmanagementconsiderations AT jessicanrichardson impactofpregnancyinpatientswiththoracicaorticdiseaseepidemiologyriskassessmentandmanagementconsiderations AT michaelnsingh impactofpregnancyinpatientswiththoracicaorticdiseaseepidemiologyriskassessmentandmanagementconsiderations |