Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment
Plant extracts have been widely considered as a feed additive. Rehmannia glutinosa catalpol can promote the growth performance of the host, improve the immune response, and strengthen the intestinal barrier function of the host. The broilers were fed with Rehmannia glutinosa catalpol (0.01%), and th...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://dx.doi.org/10.1080/1828051X.2024.2406517 |
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| author | Zhaokun Mu Liangxing Guo Yanzhou Zhou Furong Nie Zhichao Li Huan Liu Junwei Cui Minghai Huang Yi Yang |
| author_facet | Zhaokun Mu Liangxing Guo Yanzhou Zhou Furong Nie Zhichao Li Huan Liu Junwei Cui Minghai Huang Yi Yang |
| author_sort | Zhaokun Mu |
| collection | DOAJ |
| description | Plant extracts have been widely considered as a feed additive. Rehmannia glutinosa catalpol can promote the growth performance of the host, improve the immune response, and strengthen the intestinal barrier function of the host. The broilers were fed with Rehmannia glutinosa catalpol (0.01%), and the composition of caecum microbiota in broilers was explored by 16S rRNA gene sequencing. Finally, the changes of intestinal mucosa morphology and immune function were analysed by tissue staining and RT-qPCR. The proportion of thick-walled bacteria in the treatment group was higher than that in the control group. At the genus level, the relative abundance of Faecalibacterium, Paraacteroides and Barnesiella increased after the addition of Rehmannia glutinosa catalpol. The function prediction results of PICRUSt2 showed that the microbiota mainly participated in the biosynthesis and degradation/utilization/association pathway. The results of tissue staining and RT-qPCR showed that the caecum tissue morphology and immune barrier function of broilers were significantly improved after the addition of catalpol. The results of this study show that Rehmannia glutinosa catalpol in the diet may be beneficial to the intestinal health of broilers, which may be achieved by regulating the intestinal microbiota and enhancing the immune function of broilers. |
| format | Article |
| id | doaj-art-bef2e7c82d6e48c59867026ef37c8daa |
| institution | Kabale University |
| issn | 1594-4077 1828-051X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj-art-bef2e7c82d6e48c59867026ef37c8daa2025-01-02T11:34:22ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2024-12-012311611162310.1080/1828051X.2024.24065172406517Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironmentZhaokun Mu0Liangxing Guo1Yanzhou Zhou2Furong Nie3Zhichao Li4Huan Liu5Junwei Cui6Minghai Huang7Yi Yang8College of Animal Sciences, South China Agricultural UniversityHenan University of Animal Husbandry and EconomyHenan University of Animal Husbandry and EconomyHenan University of Animal Husbandry and EconomyCollege of Animal Science and Technology, Henan Agricultural UniversityHenan University of Animal Husbandry and EconomyHenan University of Animal Husbandry and EconomyHenan University of Animal Husbandry and EconomyHenan University of Animal Husbandry and EconomyPlant extracts have been widely considered as a feed additive. Rehmannia glutinosa catalpol can promote the growth performance of the host, improve the immune response, and strengthen the intestinal barrier function of the host. The broilers were fed with Rehmannia glutinosa catalpol (0.01%), and the composition of caecum microbiota in broilers was explored by 16S rRNA gene sequencing. Finally, the changes of intestinal mucosa morphology and immune function were analysed by tissue staining and RT-qPCR. The proportion of thick-walled bacteria in the treatment group was higher than that in the control group. At the genus level, the relative abundance of Faecalibacterium, Paraacteroides and Barnesiella increased after the addition of Rehmannia glutinosa catalpol. The function prediction results of PICRUSt2 showed that the microbiota mainly participated in the biosynthesis and degradation/utilization/association pathway. The results of tissue staining and RT-qPCR showed that the caecum tissue morphology and immune barrier function of broilers were significantly improved after the addition of catalpol. The results of this study show that Rehmannia glutinosa catalpol in the diet may be beneficial to the intestinal health of broilers, which may be achieved by regulating the intestinal microbiota and enhancing the immune function of broilers.http://dx.doi.org/10.1080/1828051X.2024.2406517broilersrehmannia catalpolintestinal microbiotaintestinal immunity |
| spellingShingle | Zhaokun Mu Liangxing Guo Yanzhou Zhou Furong Nie Zhichao Li Huan Liu Junwei Cui Minghai Huang Yi Yang Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment Italian Journal of Animal Science broilers rehmannia catalpol intestinal microbiota intestinal immunity |
| title | Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment |
| title_full | Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment |
| title_fullStr | Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment |
| title_full_unstemmed | Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment |
| title_short | Dietary supplementation with Rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment |
| title_sort | dietary supplementation with rehmannia glutinosa catalpol improves broiler performance by regulating intestinal immune microenvironment |
| topic | broilers rehmannia catalpol intestinal microbiota intestinal immunity |
| url | http://dx.doi.org/10.1080/1828051X.2024.2406517 |
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