Ferroptosis-associated signaling pathways and therapeutic approaches in depression

Ferroptosis, a newly identified form of cell death, is characterized by excessive iron accumulation and lipid peroxidation. Studies indicate a strong association between ferroptosis and depression; however, the precise signaling pathways and underlying molecular mechanisms remain unclear. This revie...

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Main Authors: Xuyang Feng, Wenyu Zhang, Xiaoxi Liu, Qiuxuan Wang, Xiao Dang, Jingxian Han, Xuezhu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1559597/full
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