The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane

Newcastle Disease is one of the most important disease world wide distributions which invade the flock in different age resulting in large economic losses. This study aimed to evaluate the effect of treatment with 4 different concentrations (0.25, 0.5, 1.0 and 2.0 %) of Sodium deoxycholate (SDC) on...

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Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2011-09-01
Series:مجلة بغداد للعلوم
Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1278
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description Newcastle Disease is one of the most important disease world wide distributions which invade the flock in different age resulting in large economic losses. This study aimed to evaluate the effect of treatment with 4 different concentrations (0.25, 0.5, 1.0 and 2.0 %) of Sodium deoxycholate (SDC) on the vaccinal virus (La Sota) using inoculation in the fragments of Chorioallantoic membrane. The treatment with each of the above 4 concentrations of SDC resulted in an increase in the Hemagglutination titer (HA) of the virus (28, 29.6, 211.6, 214.6) respectively as compared to the HA titer value for the untreated virus (26.6). No significant differences were noticed among all concentrations with regard to their effect on the HA titer, except the concentrations of 1.0 and 2.0 % where significant differences were recorded (P > 0.05). The results of this study suggest that SDC has an important activity in enhancement of the replication of NDV through increasing the Hemagglutination titer, which has a great importance in vaccine production.
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institution Kabale University
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2411-7986
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series مجلة بغداد للعلوم
spelling doaj-art-beecd57711244f1e8ea8b6bb1e5970402025-08-20T03:57:39ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862011-09-018310.21123/bsj.8.3.694-698The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membraneBaghdad Science JournalNewcastle Disease is one of the most important disease world wide distributions which invade the flock in different age resulting in large economic losses. This study aimed to evaluate the effect of treatment with 4 different concentrations (0.25, 0.5, 1.0 and 2.0 %) of Sodium deoxycholate (SDC) on the vaccinal virus (La Sota) using inoculation in the fragments of Chorioallantoic membrane. The treatment with each of the above 4 concentrations of SDC resulted in an increase in the Hemagglutination titer (HA) of the virus (28, 29.6, 211.6, 214.6) respectively as compared to the HA titer value for the untreated virus (26.6). No significant differences were noticed among all concentrations with regard to their effect on the HA titer, except the concentrations of 1.0 and 2.0 % where significant differences were recorded (P > 0.05). The results of this study suggest that SDC has an important activity in enhancement of the replication of NDV through increasing the Hemagglutination titer, which has a great importance in vaccine production.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1278
spellingShingle Baghdad Science Journal
The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane
مجلة بغداد للعلوم
title The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane
title_full The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane
title_fullStr The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane
title_full_unstemmed The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane
title_short The effect of Sodium deoxycholate on the production of Newcastle virus inoculated in chorioallantoic membrane
title_sort effect of sodium deoxycholate on the production of newcastle virus inoculated in chorioallantoic membrane
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1278
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