A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

Abstract The hierarchical organization of the eukaryotic genome is crucial for nuclear activities and cellular development. Genetic aberrations can disrupt this 3D genomic architecture, potentially driving oncogenesis. However, current research often lacks a comprehensive perspective, focusing on sp...

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Bibliographic Details
Main Authors: Li Tang, Matthew C. Hill, Mingxing He, Junhao Chen, Zirui Wang, Patrick T. Ellinor, Min Li
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
3D genome
cancer
Hi‐C
SNP
structure variants
Online Access:https://doi.org/10.1002/advs.202408420
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