Capabilities of Molecular Genetic Methods for Effective Hereditary Cancers Detection in Individuals with High Cancer Risk Factors

Russia and other countries report an increase in the incidence of malignant neoplasms, and approximately 10 % of all oncological cases have hereditary background. Molecular genetic testing in patients with diagnosed malignant neoplasms and a suspected hereditary factor will help to select effective...

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Main Authors: A. B. Semenova, M. M. Byakhova, V. N. Galkin, S. A. Parts, M. V. Makarova, M. V. Nemtsova, D. K. Chernevskiy, O. V. Sagaydak, E. E. Baranova, M. S. Belenikin, A. A. Krinitsina, I. E. Khatkov, N. A. Bodunova, A. M. Danishevich, D. Yu. Kanner, N. A. Savelov, A. V. Shabunin, S. S. Lebedev, D. N. Protsenko, S. M. Gadzhieva
Format: Article
Language:Russian
Published: Research Institute for Healthcare Organization and Medical Management of Moscow Healthcare Department 2023-11-01
Series:Здоровье мегаполиса
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Online Access:https://www.city-healthcare.com/jour/article/view/110
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Summary:Russia and other countries report an increase in the incidence of malignant neoplasms, and approximately 10 % of all oncological cases have hereditary background. Molecular genetic testing in patients with diagnosed malignant neoplasms and a suspected hereditary factor will help to select effective modern methods of treatment and prevention of the development of neoplasms of other localizations.According to the study, 12,6 % of patients had hereditary cancer syndrome, which allowed to administer molecular genetic tests to patients’ relatives. Consequently, it becomes possible to detect hereditary cancer risk factors, improve the efficiency of clinical examination, elaborate and implement programs for prevention and early detection of the disease.
ISSN:2713-2617