Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens

In order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. The immunomo...

Full description

Saved in:
Bibliographic Details
Main Authors: Qiuyan Sun, Fang Li, Caixia Wang, Meiyan Shen
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2019/9542759
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832553569459372032
author Qiuyan Sun
Fang Li
Caixia Wang
Meiyan Shen
author_facet Qiuyan Sun
Fang Li
Caixia Wang
Meiyan Shen
author_sort Qiuyan Sun
collection DOAJ
description In order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. The immunomodulatory efficacy of RPPS was determined by the antibody titer, the lymphocyte transformation rate in peripheral blood, the CD4+ and CD8+ T lymphocyte levels in peripheral blood, and the cytokine levels in the serum. The results showed that RPPS could not only enhance the immune effect of IB live vaccine but also improve the immunity of immunosuppressive chickens. Thus, the function of RPPS immunopotentiator could be further developed.
format Article
id doaj-art-bedf783b372a4efb9c491f417e178d20
institution Kabale University
issn 1687-9422
1687-9430
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series International Journal of Polymer Science
spelling doaj-art-bedf783b372a4efb9c491f417e178d202025-02-03T05:53:43ZengWileyInternational Journal of Polymer Science1687-94221687-94302019-01-01201910.1155/2019/95427599542759Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive ChickensQiuyan Sun0Fang Li1Caixia Wang2Meiyan Shen3Department of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaDepartment of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaDepartment of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaDepartment of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaIn order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. The immunomodulatory efficacy of RPPS was determined by the antibody titer, the lymphocyte transformation rate in peripheral blood, the CD4+ and CD8+ T lymphocyte levels in peripheral blood, and the cytokine levels in the serum. The results showed that RPPS could not only enhance the immune effect of IB live vaccine but also improve the immunity of immunosuppressive chickens. Thus, the function of RPPS immunopotentiator could be further developed.http://dx.doi.org/10.1155/2019/9542759
spellingShingle Qiuyan Sun
Fang Li
Caixia Wang
Meiyan Shen
Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
International Journal of Polymer Science
title Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
title_full Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
title_fullStr Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
title_full_unstemmed Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
title_short Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
title_sort immunomodulatory effects of robinia pseudoacacia polysaccharides on live vaccine against infectious bronchitis in immunosuppressive chickens
url http://dx.doi.org/10.1155/2019/9542759
work_keys_str_mv AT qiuyansun immunomodulatoryeffectsofrobiniapseudoacaciapolysaccharidesonlivevaccineagainstinfectiousbronchitisinimmunosuppressivechickens
AT fangli immunomodulatoryeffectsofrobiniapseudoacaciapolysaccharidesonlivevaccineagainstinfectiousbronchitisinimmunosuppressivechickens
AT caixiawang immunomodulatoryeffectsofrobiniapseudoacaciapolysaccharidesonlivevaccineagainstinfectiousbronchitisinimmunosuppressivechickens
AT meiyanshen immunomodulatoryeffectsofrobiniapseudoacaciapolysaccharidesonlivevaccineagainstinfectiousbronchitisinimmunosuppressivechickens