Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens
In order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. The immunomo...
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Wiley
2019-01-01
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Series: | International Journal of Polymer Science |
Online Access: | http://dx.doi.org/10.1155/2019/9542759 |
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author | Qiuyan Sun Fang Li Caixia Wang Meiyan Shen |
author_facet | Qiuyan Sun Fang Li Caixia Wang Meiyan Shen |
author_sort | Qiuyan Sun |
collection | DOAJ |
description | In order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. The immunomodulatory efficacy of RPPS was determined by the antibody titer, the lymphocyte transformation rate in peripheral blood, the CD4+ and CD8+ T lymphocyte levels in peripheral blood, and the cytokine levels in the serum. The results showed that RPPS could not only enhance the immune effect of IB live vaccine but also improve the immunity of immunosuppressive chickens. Thus, the function of RPPS immunopotentiator could be further developed. |
format | Article |
id | doaj-art-bedf783b372a4efb9c491f417e178d20 |
institution | Kabale University |
issn | 1687-9422 1687-9430 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Polymer Science |
spelling | doaj-art-bedf783b372a4efb9c491f417e178d202025-02-03T05:53:43ZengWileyInternational Journal of Polymer Science1687-94221687-94302019-01-01201910.1155/2019/95427599542759Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive ChickensQiuyan Sun0Fang Li1Caixia Wang2Meiyan Shen3Department of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaDepartment of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaDepartment of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaDepartment of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang 261061, ChinaIn order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. The immunomodulatory efficacy of RPPS was determined by the antibody titer, the lymphocyte transformation rate in peripheral blood, the CD4+ and CD8+ T lymphocyte levels in peripheral blood, and the cytokine levels in the serum. The results showed that RPPS could not only enhance the immune effect of IB live vaccine but also improve the immunity of immunosuppressive chickens. Thus, the function of RPPS immunopotentiator could be further developed.http://dx.doi.org/10.1155/2019/9542759 |
spellingShingle | Qiuyan Sun Fang Li Caixia Wang Meiyan Shen Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens International Journal of Polymer Science |
title | Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens |
title_full | Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens |
title_fullStr | Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens |
title_full_unstemmed | Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens |
title_short | Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens |
title_sort | immunomodulatory effects of robinia pseudoacacia polysaccharides on live vaccine against infectious bronchitis in immunosuppressive chickens |
url | http://dx.doi.org/10.1155/2019/9542759 |
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