Improving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity
IntroductionMSCs exhibit regenerative, anti-inflammatory and immunomodulatory properties due to the large amount of cytokines, chemokines and growth factors they secrete. MSCs have been extensively evaluated in clinical trials, however, in some cases their therapeutic effects are variable. Therefore...
Saved in:
| Main Authors: | Jaris Valencia, Rosa M. Yáñez, Sandra Muntión, María Fernández-García, Jorge Diego Martín-Rufino, Agustín G. Zapata, Juan A. Bueren, Ángeles Vicente, Fermín Sánchez-Guijo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-02-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1473788/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of a strength physical exercise program in chronic lymphocytic leukemia patients on quality of life, mental health, and frailty: a randomized controlled trial study protocol
by: Juan Luis Sánchez-González, et al.
Published: (2025-03-01) -
Effect of Hyaluronic Acid Compared to Platelet-Rich Plasma as Adjuvants to Bone Marrow Mesenchymal Stem Cell Treatment of Knee Osteoarthritis: Analysis from Two Clinical Trials
by: José María Lamo-Espinosa, et al.
Published: (2025-01-01) -
Mesenchymal stromal cells (MSC) from JAK2+ myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesis.
by: Teresa L Ramos, et al.
Published: (2017-01-01) -
Intrastromal autologous implantation of adipose derived adult stem cells for the management of established corneal scars
by: Jorge L. Alio del Barrio, et al.
Published: (2025-03-01) -
The inconclusive superiority debate of allogeneic versus autologous MSCs in treating patients with HFrEF: a systematic review and meta-analysis of RCTs
by: Omar T. F. Ahmed, et al.
Published: (2025-04-01)