Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report

Primary Sjögren syndrome (PSS) as a chronic systemic autoimmune disease, many patients with early hidden symptoms of presented the clinical manifestations of other systemic diseases for the first time, and its pathogenesis was not clear yet. PSS could invade the exocrine glands of body, and the kidn...

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Main Author: HUANG Min, ZUO Ying
Format: Article
Language:zho
Published: Editorial Office of Journal of Diagnostics Concepts & Practice 2024-12-01
Series:Zhenduanxue lilun yu shijian
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Online Access:https://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1740725538035-1001598705.pdf
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author HUANG Min, ZUO Ying
author_facet HUANG Min, ZUO Ying
author_sort HUANG Min, ZUO Ying
collection DOAJ
description Primary Sjögren syndrome (PSS) as a chronic systemic autoimmune disease, many patients with early hidden symptoms of presented the clinical manifestations of other systemic diseases for the first time, and its pathogenesis was not clear yet. PSS could invade the exocrine glands of body, and the kidney was also the susceptible organ in PSS. Some patients could develop to renal tubular acidosis, and lead to refractory hypokalemia and related clinical manifestations. As lack of effective treatment, the early diagnosis and intervention of the disease could avoid damage or delay the involvement of related organs and maximize the benefits of clinical treatment. This paper reported a patient, who was admitted to hospital with chief complain of repeated limb weakness for one year, was diagnosed as type I renal tubular acidosis secondary to primary Sjögren syndrome. The patients received symptomatic treatment and hydroxychloroquine sulfate immunotherapy, and the symptoms were resolved eventually.
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publisher Editorial Office of Journal of Diagnostics Concepts & Practice
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spelling doaj-art-bed7c7deb3ee4b5e84bf80a865d5b1dc2025-08-20T01:47:53ZzhoEditorial Office of Journal of Diagnostics Concepts & PracticeZhenduanxue lilun yu shijian1671-28702024-12-01230662462710.16150/j.1671-2870.2024.06.010Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case reportHUANG Min, ZUO Ying01. Graduate school of North Sichuan Medical College, Sichuan Nanchong 637000, China;2. Department of Endocrinology and Metabolism, The Affiliated Hospital of North Sichuan Medical College, Sichuan Nanchong 637000, ChinaPrimary Sjögren syndrome (PSS) as a chronic systemic autoimmune disease, many patients with early hidden symptoms of presented the clinical manifestations of other systemic diseases for the first time, and its pathogenesis was not clear yet. PSS could invade the exocrine glands of body, and the kidney was also the susceptible organ in PSS. Some patients could develop to renal tubular acidosis, and lead to refractory hypokalemia and related clinical manifestations. As lack of effective treatment, the early diagnosis and intervention of the disease could avoid damage or delay the involvement of related organs and maximize the benefits of clinical treatment. This paper reported a patient, who was admitted to hospital with chief complain of repeated limb weakness for one year, was diagnosed as type I renal tubular acidosis secondary to primary Sjögren syndrome. The patients received symptomatic treatment and hydroxychloroquine sulfate immunotherapy, and the symptoms were resolved eventually.https://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1740725538035-1001598705.pdf|primary sjögren syndrome|renal tubular acidosis|hypokalemia|diagnosis
spellingShingle HUANG Min, ZUO Ying
Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report
Zhenduanxue lilun yu shijian
|primary sjögren syndrome|renal tubular acidosis|hypokalemia|diagnosis
title Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report
title_full Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report
title_fullStr Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report
title_full_unstemmed Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report
title_short Type Ⅰ renal tubular acidosis caused by primary Sjögren syndrome with first diagnosis of hypokalemia: a case report
title_sort type i renal tubular acidosis caused by primary sjogren syndrome with first diagnosis of hypokalemia a case report
topic |primary sjögren syndrome|renal tubular acidosis|hypokalemia|diagnosis
url https://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1740725538035-1001598705.pdf
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