INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS
Abstract. The article contains results of studying the natural inhibitory serum activity in the patients with acute leukemia. A correlation is revealed between a resistance to myelosuppressive therapy, and positive inhibitory reaction towards immunoglobulins M. Determination of IL-2, IL-4 levels, as...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/373 |
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| author | G. M. Chernousova N. К. Rodosskaya |
| author_facet | G. M. Chernousova N. К. Rodosskaya |
| author_sort | G. M. Chernousova |
| collection | DOAJ |
| description | Abstract. The article contains results of studying the natural inhibitory serum activity in the patients with acute leukemia. A correlation is revealed between a resistance to myelosuppressive therapy, and positive inhibitory reaction towards immunoglobulins M. Determination of IL-2, IL-4 levels, as well as sulfhydril (SH- ) groups and amounts of blast cells at initial stage of disease are of high importance for early diagnosis of drug resistance upon the disease onset. |
| format | Article |
| id | doaj-art-bec28da3673343e781c5590dec94cbb8 |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-bec28da3673343e781c5590dec94cbb82025-08-20T03:37:46ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0111657758010.15789/1563-0625-2009-6-577-580370INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTSG. M. Chernousova0N. К. Rodosskaya1Воронежская областная клиническая больница № 1, г. ВоронежВоронежская государственная медицинская академия им. Н.Н. Бурденко, г. ВоронежAbstract. The article contains results of studying the natural inhibitory serum activity in the patients with acute leukemia. A correlation is revealed between a resistance to myelosuppressive therapy, and positive inhibitory reaction towards immunoglobulins M. Determination of IL-2, IL-4 levels, as well as sulfhydril (SH- ) groups and amounts of blast cells at initial stage of disease are of high importance for early diagnosis of drug resistance upon the disease onset.https://www.mimmun.ru/mimmun/article/view/373natural inhibitory activityblood serumsh-groupsil-2il-4 |
| spellingShingle | G. M. Chernousova N. К. Rodosskaya INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS Медицинская иммунология natural inhibitory activity blood serum sh-groups il-2 il-4 |
| title | INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS |
| title_full | INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS |
| title_fullStr | INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS |
| title_full_unstemmed | INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS |
| title_short | INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS |
| title_sort | investigation of natural inhibitory activity of blood serum in acute leukemia patients |
| topic | natural inhibitory activity blood serum sh-groups il-2 il-4 |
| url | https://www.mimmun.ru/mimmun/article/view/373 |
| work_keys_str_mv | AT gmchernousova investigationofnaturalinhibitoryactivityofbloodseruminacuteleukemiapatients AT nkrodosskaya investigationofnaturalinhibitoryactivityofbloodseruminacuteleukemiapatients |