Neutrophil-induced pyroptosis promotes survival in patients with hepatoblastoma

Neutrophil-induced pyroptosis promotes survival in patients with hepatoblastoma

Abstract Background Hepatoblastoma (HB) is the predominant hepatic malignancy among children. Despite therapeutic options for HB were gradually refined in recent years, patients with metastasis suffer from an unsatisfactory prognosis. Pyroptosis is a type of programmed and inflammatory necrosis. Neu...

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Main Authors: Tingyi Fu, Jiquan Zhou, Liyuan Yang, Jing Wang, Hui Li, Yuhua Shan, Hongxiang Gao, Chenjie Xie, Dapeng Jiang, Lei Zhang, Ji Ma, Qiuhui Pan, Min Xu, Min Zhang, Song Gu
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Hepatoblastoma
Pyroptosis
ELANE
Neutrophil
Neutrophil extracellular traps
Online Access:https://doi.org/10.1007/s00262-024-03922-z
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