Artificial intelligence in the discovery and modification of biological elements in medicinal plants

Active ingredients extracted from medicinal plants are important natural sources in the field of pharmaceutical and industrial products. However, the low abundance and quality of these compounds have consistently posed a significant barrier to the full utilization of these ingredients. The discovery...

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Main Authors: Jing Zhang, Yixin Yang, Jinping Si, Donghong Chen, Chuan Dong, Zhigang Han
Format: Article
Language:English
Published: Maximum Academic Press 2025-01-01
Series:Medicinal Plant Biology
Subjects:
Online Access:https://www.maxapress.com/article/doi/10.48130/mpb-0025-0010
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author Jing Zhang
Yixin Yang
Jinping Si
Donghong Chen
Chuan Dong
Zhigang Han
author_facet Jing Zhang
Yixin Yang
Jinping Si
Donghong Chen
Chuan Dong
Zhigang Han
author_sort Jing Zhang
collection DOAJ
description Active ingredients extracted from medicinal plants are important natural sources in the field of pharmaceutical and industrial products. However, the low abundance and quality of these compounds have consistently posed a significant barrier to the full utilization of these ingredients. The discovery of enzymes in related pathways, enzyme activity modification, and pathway optimization are key to solving this problem. The emergence of large-scale multi-omics data has provided new opportunities to enhance this progress. But a new big challenge in analyzing the massive amounts of biological data lies before us. Artificial intelligence (AI) is state of the art for its process in big data and pattern recognition that has already had a revolutionary impact on biological fields. Here, we summarize recent advancements in pathway analysis and research ideas in AI-mediated discovery and modification of biological elements. Future directions and challenges for applying AI in precision medicinal plant breeding, and the biosynthesis of optimized, stable, and cost-effective natural products are also discussed.
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publishDate 2025-01-01
publisher Maximum Academic Press
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series Medicinal Plant Biology
spelling doaj-art-beb953096eb24135a1a4d42a0d3d70352025-08-20T03:18:23ZengMaximum Academic PressMedicinal Plant Biology2835-69692025-01-01411810.48130/mpb-0025-0010mpb-0025-0010Artificial intelligence in the discovery and modification of biological elements in medicinal plantsJing Zhang0Yixin Yang1Jinping Si2Donghong Chen3Chuan Dong4Zhigang Han5National Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, ChinaActive ingredients extracted from medicinal plants are important natural sources in the field of pharmaceutical and industrial products. However, the low abundance and quality of these compounds have consistently posed a significant barrier to the full utilization of these ingredients. The discovery of enzymes in related pathways, enzyme activity modification, and pathway optimization are key to solving this problem. The emergence of large-scale multi-omics data has provided new opportunities to enhance this progress. But a new big challenge in analyzing the massive amounts of biological data lies before us. Artificial intelligence (AI) is state of the art for its process in big data and pattern recognition that has already had a revolutionary impact on biological fields. Here, we summarize recent advancements in pathway analysis and research ideas in AI-mediated discovery and modification of biological elements. Future directions and challenges for applying AI in precision medicinal plant breeding, and the biosynthesis of optimized, stable, and cost-effective natural products are also discussed.https://www.maxapress.com/article/doi/10.48130/mpb-0025-0010artificial intelligencemedicinal plantsenzyme discoveryenzyme modification
spellingShingle Jing Zhang
Yixin Yang
Jinping Si
Donghong Chen
Chuan Dong
Zhigang Han
Artificial intelligence in the discovery and modification of biological elements in medicinal plants
Medicinal Plant Biology
artificial intelligence
medicinal plants
enzyme discovery
enzyme modification
title Artificial intelligence in the discovery and modification of biological elements in medicinal plants
title_full Artificial intelligence in the discovery and modification of biological elements in medicinal plants
title_fullStr Artificial intelligence in the discovery and modification of biological elements in medicinal plants
title_full_unstemmed Artificial intelligence in the discovery and modification of biological elements in medicinal plants
title_short Artificial intelligence in the discovery and modification of biological elements in medicinal plants
title_sort artificial intelligence in the discovery and modification of biological elements in medicinal plants
topic artificial intelligence
medicinal plants
enzyme discovery
enzyme modification
url https://www.maxapress.com/article/doi/10.48130/mpb-0025-0010
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AT jinpingsi artificialintelligenceinthediscoveryandmodificationofbiologicalelementsinmedicinalplants
AT donghongchen artificialintelligenceinthediscoveryandmodificationofbiologicalelementsinmedicinalplants
AT chuandong artificialintelligenceinthediscoveryandmodificationofbiologicalelementsinmedicinalplants
AT zhiganghan artificialintelligenceinthediscoveryandmodificationofbiologicalelementsinmedicinalplants