The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection
Endometritis is a very common pathology in animals which changes endometrial leukotriene (LT) formation and muscarinic 2 and 3 receptor subtypes (M2R/M3R) and α-7 nicotinic acetylcholine (ACh) receptor (α-7 nAChR) expression patterns. With the relationship between ACh, its receptors and LT productio...
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| Format: | Article |
| Language: | English |
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Sciendo
2024-11-01
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| Series: | Journal of Veterinary Research |
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| Online Access: | https://doi.org/10.2478/jvetres-2024-0066 |
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| author | Jana Barbara Całka Jarosław Bulc Michał Kawka Dominika |
| author_facet | Jana Barbara Całka Jarosław Bulc Michał Kawka Dominika |
| author_sort | Jana Barbara |
| collection | DOAJ |
| description | Endometritis is a very common pathology in animals which changes endometrial leukotriene (LT) formation and muscarinic 2 and 3 receptor subtypes (M2R/M3R) and α-7 nicotinic acetylcholine (ACh) receptor (α-7 nAChR) expression patterns. With the relationship between ACh, its receptors and LT production remaining unclear, the role of M2R, M3R and α-7 nAChR in action of ACh on the 5-lipoxygenase (5-LO), LTA4 hydrolase (LTAH) and LTC4 synthase (LTCS) protein abundances in the inflamed porcine endometrium and on the tissue secretion of LTB4 and LTC4 were studied. |
| format | Article |
| id | doaj-art-beb64850d61d441692ce144313c7e00b |
| institution | Kabale University |
| issn | 2450-8608 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Veterinary Research |
| spelling | doaj-art-beb64850d61d441692ce144313c7e00b2025-01-07T07:56:37ZengSciendoJournal of Veterinary Research2450-86082024-11-0168457158110.2478/jvetres-2024-0066The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infectionJana Barbara0Całka Jarosław1Bulc Michał2Kawka Dominika31Division of Reproductive Biology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, 10-748Olsztyn, Poland2Department of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, 10-718Olsztyn, Poland2Department of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, 10-718Olsztyn, Poland1Division of Reproductive Biology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, 10-748Olsztyn, PolandEndometritis is a very common pathology in animals which changes endometrial leukotriene (LT) formation and muscarinic 2 and 3 receptor subtypes (M2R/M3R) and α-7 nicotinic acetylcholine (ACh) receptor (α-7 nAChR) expression patterns. With the relationship between ACh, its receptors and LT production remaining unclear, the role of M2R, M3R and α-7 nAChR in action of ACh on the 5-lipoxygenase (5-LO), LTA4 hydrolase (LTAH) and LTC4 synthase (LTCS) protein abundances in the inflamed porcine endometrium and on the tissue secretion of LTB4 and LTC4 were studied.https://doi.org/10.2478/jvetres-2024-0066endometritisacetylcholineb4 and c4 leukotriene productionpig |
| spellingShingle | Jana Barbara Całka Jarosław Bulc Michał Kawka Dominika The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection Journal of Veterinary Research endometritis acetylcholine b4 and c4 leukotriene production pig |
| title | The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection |
| title_full | The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection |
| title_fullStr | The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection |
| title_full_unstemmed | The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection |
| title_short | The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection |
| title_sort | regulatory action of acetylcholine and its receptors on b4 and c4 leukotriene formation in the porcine endometrium after experimental inflammogenic escherichia coli infection |
| topic | endometritis acetylcholine b4 and c4 leukotriene production pig |
| url | https://doi.org/10.2478/jvetres-2024-0066 |
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