Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence

Abstract Background Mosquitoes are important drivers of infectious diseases transmission, with Anopheles mosquitoes being responsible of malaria transmission. In Cambodia, where malaria is prevalent in forested regions, understanding the ecology of these vectors is crucial. This study aimed to inves...

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Main Authors: Sebastien Boyer, Bros Doeurk, Antsa Rakotonirina, Sophy Chy, Chantrea Vong, Eakpor Piv, Baura Tat, Malen Ea, Chansophea Chhin, Sreyvouch Phen, Nimol Kloeung, Sopheakvatey Ke, Jean Popovici, Patrice Piola, Benoit Witkowski, Pierre-Olivier Maquart, Amélie Vantaux
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Malaria Journal
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Online Access:https://doi.org/10.1186/s12936-024-05166-9
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author Sebastien Boyer
Bros Doeurk
Antsa Rakotonirina
Sophy Chy
Chantrea Vong
Eakpor Piv
Baura Tat
Malen Ea
Chansophea Chhin
Sreyvouch Phen
Nimol Kloeung
Sopheakvatey Ke
Jean Popovici
Patrice Piola
Benoit Witkowski
Pierre-Olivier Maquart
Amélie Vantaux
author_facet Sebastien Boyer
Bros Doeurk
Antsa Rakotonirina
Sophy Chy
Chantrea Vong
Eakpor Piv
Baura Tat
Malen Ea
Chansophea Chhin
Sreyvouch Phen
Nimol Kloeung
Sopheakvatey Ke
Jean Popovici
Patrice Piola
Benoit Witkowski
Pierre-Olivier Maquart
Amélie Vantaux
author_sort Sebastien Boyer
collection DOAJ
description Abstract Background Mosquitoes are important drivers of infectious diseases transmission, with Anopheles mosquitoes being responsible of malaria transmission. In Cambodia, where malaria is prevalent in forested regions, understanding the ecology of these vectors is crucial. This study aimed to investigate the abundance, distribution, seasonal patterns, biting behaviour of Anopheles mosquitoes, and prevalence of Plasmodium, in Mondulkiri province, Northeastern Cambodia. Methods Conducted in 9 sites, seven in forested and two in neighbouring villages, over one year, the collection of Anopheles mosquitoes was made hourly for a 72-h period every month, using a human-baited double net trap. Each mosquito was collected using a mouth-aspirator and identified morphologically, and screened for the presence of Plasmodium. Results Primary vectors, including Anopheles baimaii, Anopheles dirus, Anopheles maculatus, and Anopheles minimus, constituted 11.1% of all female mosquitoes, while 12 secondary vector species represented 29.4% of the overall collection. Anopheles species were more prevalent during the late rainy season (August to November), with year-round activity observed. Primary vectors were predominantly found in forest sites, while other vector species were found in both village and forest environments. Notably, primary vectors exhibited a preference for nocturnal biting, yet a significant proportion (19.2%) displayed daytime activity, highlighting a potential risk of daytime malaria transmission. Among 5,056 Anopheles specimens tested, only 36 Plasmodium spp.-infected samples were detected, mainly in forest sites (94%), and in specimens collected at night. This study provides essential insights into the ecology of Anopheles in Mondulkiri Forest. Conclusions The identification of primary and secondary vectors, their seasonal dynamics, and biting behaviour contribute to enhances our understanding of malaria transmission risks in these areas, guiding future strategies toward effective and context-specific control measures, while stressing the need for individual protection during daytime.
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spelling doaj-art-beb646ba47554b2e8bed416ef7ad53682025-08-20T02:36:30ZengBMCMalaria Journal1475-28752025-01-0124111210.1186/s12936-024-05166-9Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalenceSebastien Boyer0Bros Doeurk1Antsa Rakotonirina2Sophy Chy3Chantrea Vong4Eakpor Piv5Baura Tat6Malen Ea7Chansophea Chhin8Sreyvouch Phen9Nimol Kloeung10Sopheakvatey Ke11Jean Popovici12Patrice Piola13Benoit Witkowski14Pierre-Olivier Maquart15Amélie Vantaux16Medical and Veterinary Entomology Unit, Institut Pasteur du CambodgeMedical and Veterinary Entomology Unit, Institut Pasteur du CambodgeMedical and Veterinary Entomology Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeEpidemiology and Public Health Unit, Institute Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeMedical and Veterinary Entomology Unit, Institut Pasteur du CambodgeMalaria Research Unit, Institut Pasteur du CambodgeAbstract Background Mosquitoes are important drivers of infectious diseases transmission, with Anopheles mosquitoes being responsible of malaria transmission. In Cambodia, where malaria is prevalent in forested regions, understanding the ecology of these vectors is crucial. This study aimed to investigate the abundance, distribution, seasonal patterns, biting behaviour of Anopheles mosquitoes, and prevalence of Plasmodium, in Mondulkiri province, Northeastern Cambodia. Methods Conducted in 9 sites, seven in forested and two in neighbouring villages, over one year, the collection of Anopheles mosquitoes was made hourly for a 72-h period every month, using a human-baited double net trap. Each mosquito was collected using a mouth-aspirator and identified morphologically, and screened for the presence of Plasmodium. Results Primary vectors, including Anopheles baimaii, Anopheles dirus, Anopheles maculatus, and Anopheles minimus, constituted 11.1% of all female mosquitoes, while 12 secondary vector species represented 29.4% of the overall collection. Anopheles species were more prevalent during the late rainy season (August to November), with year-round activity observed. Primary vectors were predominantly found in forest sites, while other vector species were found in both village and forest environments. Notably, primary vectors exhibited a preference for nocturnal biting, yet a significant proportion (19.2%) displayed daytime activity, highlighting a potential risk of daytime malaria transmission. Among 5,056 Anopheles specimens tested, only 36 Plasmodium spp.-infected samples were detected, mainly in forest sites (94%), and in specimens collected at night. This study provides essential insights into the ecology of Anopheles in Mondulkiri Forest. Conclusions The identification of primary and secondary vectors, their seasonal dynamics, and biting behaviour contribute to enhances our understanding of malaria transmission risks in these areas, guiding future strategies toward effective and context-specific control measures, while stressing the need for individual protection during daytime.https://doi.org/10.1186/s12936-024-05166-9AnophelesPlasmodiumBiologyBiting behavior
spellingShingle Sebastien Boyer
Bros Doeurk
Antsa Rakotonirina
Sophy Chy
Chantrea Vong
Eakpor Piv
Baura Tat
Malen Ea
Chansophea Chhin
Sreyvouch Phen
Nimol Kloeung
Sopheakvatey Ke
Jean Popovici
Patrice Piola
Benoit Witkowski
Pierre-Olivier Maquart
Amélie Vantaux
Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
Malaria Journal
Anopheles
Plasmodium
Biology
Biting behavior
title Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
title_full Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
title_fullStr Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
title_full_unstemmed Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
title_short Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
title_sort anopheles mosquitoes in mondulkiri forest cambodia abundance distribution seasonal patterns and plasmodium prevalence
topic Anopheles
Plasmodium
Biology
Biting behavior
url https://doi.org/10.1186/s12936-024-05166-9
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