Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients
The base deficit (B), international normalized ratio (I), and Glasgow coma scale (GCS) (BIG) score is useful in predicting mortality in pediatric trauma patients; however, studies on the use of BIG score in adult patients with trauma are sparse. In addition, studies on the correlation between the BI...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-01-01
|
| Series: | Emergency Medicine International |
| Online Access: | http://dx.doi.org/10.1155/2023/5162050 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850179012120281088 |
|---|---|
| author | Sejun Park Il Jae Wang Seok-Ran Yeom Sung-Wook Park Suck Ju Cho Wook Tae Yang Wonwoong Tae Up Huh Chanhee Song Yeaeun Kim Jong-Hwan Park Youngmo Cho |
| author_facet | Sejun Park Il Jae Wang Seok-Ran Yeom Sung-Wook Park Suck Ju Cho Wook Tae Yang Wonwoong Tae Up Huh Chanhee Song Yeaeun Kim Jong-Hwan Park Youngmo Cho |
| author_sort | Sejun Park |
| collection | DOAJ |
| description | The base deficit (B), international normalized ratio (I), and Glasgow coma scale (GCS) (BIG) score is useful in predicting mortality in pediatric trauma patients; however, studies on the use of BIG score in adult patients with trauma are sparse. In addition, studies on the correlation between the BIG score and massive transfusion (MT) have not yet been conducted. This study aimed to evaluate the predictive value of BIG score for mortality and the need for MT in adult trauma patients. This retrospective study used data collected between 2016 and 2020 at our hospital’s trauma center and registry. The predictive value of BIG score was compared with that of the Injury Severity Score (ISS) and Revised Trauma Score (RTS). Logistic regression analysis was carried out to assess whether BIG score was an independent risk factor. Receiver operating characteristic (ROC) curve analysis was performed, and predictive values were evaluated by measuring the area under the ROC curve (AUROC). In total, 5,605 patients were included in this study. In logistic regression analysis, BIG score was independently associated with in-hospital mortality (odds ratio (OR): 1.1859; 95% confidence interval (CI): 1.1636–1.2086) and MT (OR: 1.0802; 95% CI: 1.0609–1.0999). The AUROCs of BIG score for in-hospital mortality and MT were 0.852 (0.842–0.861) and 0.848 (0.838–0.857), respectively. Contrastingly, the AUROCs of ISS and RTS for in-hospital mortality were 0.795 (0.784–0.805) and 0.859 (0.850–0.868), respectively. Moreover, AUROCs of ISS and RTS for MT were 0.812 (0.802–0.822) and 0.838 (0.828–0.848), respectively. The predictive value of BIG score for mortality and MT was significantly higher than that of the ISS. The BIG score also showed a better AUROC for predicting in-hospital mortality compared with RTS. In conclusion, the BIG score is a useful indicator for predicting mortality and the need for MT in adult trauma patients. |
| format | Article |
| id | doaj-art-beb5400d73dd42cabfb606e2cf981747 |
| institution | OA Journals |
| issn | 2090-2859 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Emergency Medicine International |
| spelling | doaj-art-beb5400d73dd42cabfb606e2cf9817472025-08-20T02:18:35ZengWileyEmergency Medicine International2090-28592023-01-01202310.1155/2023/5162050Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma PatientsSejun Park0Il Jae Wang1Seok-Ran Yeom2Sung-Wook Park3Suck Ju Cho4Wook Tae Yang5Wonwoong Tae6Up Huh7Chanhee Song8Yeaeun Kim9Jong-Hwan Park10Youngmo Cho11Department of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Thoracic and Cardiovascular SurgeryMedical Research InstituteDepartment of Health Care ManagementHealth Convergence Medicine LaboratoryDepartment of Emergency MedicineThe base deficit (B), international normalized ratio (I), and Glasgow coma scale (GCS) (BIG) score is useful in predicting mortality in pediatric trauma patients; however, studies on the use of BIG score in adult patients with trauma are sparse. In addition, studies on the correlation between the BIG score and massive transfusion (MT) have not yet been conducted. This study aimed to evaluate the predictive value of BIG score for mortality and the need for MT in adult trauma patients. This retrospective study used data collected between 2016 and 2020 at our hospital’s trauma center and registry. The predictive value of BIG score was compared with that of the Injury Severity Score (ISS) and Revised Trauma Score (RTS). Logistic regression analysis was carried out to assess whether BIG score was an independent risk factor. Receiver operating characteristic (ROC) curve analysis was performed, and predictive values were evaluated by measuring the area under the ROC curve (AUROC). In total, 5,605 patients were included in this study. In logistic regression analysis, BIG score was independently associated with in-hospital mortality (odds ratio (OR): 1.1859; 95% confidence interval (CI): 1.1636–1.2086) and MT (OR: 1.0802; 95% CI: 1.0609–1.0999). The AUROCs of BIG score for in-hospital mortality and MT were 0.852 (0.842–0.861) and 0.848 (0.838–0.857), respectively. Contrastingly, the AUROCs of ISS and RTS for in-hospital mortality were 0.795 (0.784–0.805) and 0.859 (0.850–0.868), respectively. Moreover, AUROCs of ISS and RTS for MT were 0.812 (0.802–0.822) and 0.838 (0.828–0.848), respectively. The predictive value of BIG score for mortality and MT was significantly higher than that of the ISS. The BIG score also showed a better AUROC for predicting in-hospital mortality compared with RTS. In conclusion, the BIG score is a useful indicator for predicting mortality and the need for MT in adult trauma patients.http://dx.doi.org/10.1155/2023/5162050 |
| spellingShingle | Sejun Park Il Jae Wang Seok-Ran Yeom Sung-Wook Park Suck Ju Cho Wook Tae Yang Wonwoong Tae Up Huh Chanhee Song Yeaeun Kim Jong-Hwan Park Youngmo Cho Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients Emergency Medicine International |
| title | Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients |
| title_full | Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients |
| title_fullStr | Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients |
| title_full_unstemmed | Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients |
| title_short | Usefulness of the BIG Score in Predicting Massive Transfusion and In-Hospital Death in Adult Trauma Patients |
| title_sort | usefulness of the big score in predicting massive transfusion and in hospital death in adult trauma patients |
| url | http://dx.doi.org/10.1155/2023/5162050 |
| work_keys_str_mv | AT sejunpark usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT iljaewang usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT seokranyeom usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT sungwookpark usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT suckjucho usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT wooktaeyang usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT wonwoongtae usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT uphuh usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT chanheesong usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT yeaeunkim usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT jonghwanpark usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients AT youngmocho usefulnessofthebigscoreinpredictingmassivetransfusionandinhospitaldeathinadulttraumapatients |