Molecular characterization of colorectal cancer (CRC) using next generation sequencing (NGS) in bridging the gap between research and clinical practice: from biomarker discovery to clinical implementation

Molecular characterization of colorectal cancer (CRC) using next generation sequencing (NGS) in bridging the gap between research and clinical practice: from biomarker discovery to clinical implementation

Abstract Background Colorectal cancer (CRC) is the second most common cancer in men and third in females, a heterogeneous disease involving multistep mechanisms that represents 10% of all cancers globally. This study investigates gene mutation profiling in CRC using Next-Generation sequencing machin...

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Bibliographic Details
Main Authors: Hafeez Abiola Afolabi, Salzihan Md Salleh, Zaidi Zakaria, Ch’ng Ewe Seng, Siti Norasikin Mohd Nafi, Ahmad Aizat Bin Abdul Aziz, Wan Mohd Nazri Wan Zainon, Ahmad Adebayo Irekola, Yusuf Wada, Sameer Badri Al-Mhanna, Rashidat Folashade Elesho
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Discover Oncology
Subjects:
Colon cancer
Colorectal carcinoma
CRC
Gene mutation profiling
Next-generation sequencing
Online Access:https://doi.org/10.1007/s12672-025-01960-2
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