The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review
Purpose: The purpose of this review is to analise current scientific literature regarding the impact of glutamine supplementation on muscle repair, post-exercise recovery, and skeletal muscle preservation. It also examines the biological pathways through which glutamine may exert its effects, i...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-04-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/59797 |
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| author | Aneta Redner Julia Głowacz Michał Popiel Klaudia Kulig Maksymilian Wiśniowski Kamil Dziekoński Jakub Rybowski Patrycja Zwierzchlewska Kacper Buczek Hubert Gorycki Dominik Stanibuła |
| author_facet | Aneta Redner Julia Głowacz Michał Popiel Klaudia Kulig Maksymilian Wiśniowski Kamil Dziekoński Jakub Rybowski Patrycja Zwierzchlewska Kacper Buczek Hubert Gorycki Dominik Stanibuła |
| author_sort | Aneta Redner |
| collection | DOAJ |
| description |
Purpose:
The purpose of this review is to analise current scientific literature regarding the impact of glutamine supplementation on muscle repair, post-exercise recovery, and skeletal muscle preservation. It also examines the biological pathways through which glutamine may exert its effects, including modulation of inflammation and enhancement of protein turnover.
Methodology:
A review of scientific literature was performed, focusing on studies investigating the effects of glutamine supplementation on skeletal muscle recovery and function. The review includes experimental studies, clinical trials, and narrative reviews involving both athletic and clinical populations, with attention to various training conditions, health statuses, and supplementation strategies.
Findings:
The evidence indicates that glutamine can support recovery processes by mitigating muscle inflammation, improving redox balance, and promoting anabolic signalling. However, the degree of effectiveness varies, with more pronounced benefits observed in clinical and stress-related conditions compared to healthy individuals. The influence of dosage, supplementation timing, and individual variability remains a key consideration.
Conclusions:
Glutamine shows potential as a supportive agent in muscle regeneration, particularly in contexts of physical stress, illness, or injury. Further studies are needed to define its role in athletic, healthy populations and to optimize administration strategies based on individual needs and health status.
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| format | Article |
| id | doaj-art-beaa3c4b59914bd8a9a4c51b5f8c231e |
| institution | OA Journals |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-beaa3c4b59914bd8a9a4c51b5f8c231e2025-08-20T02:16:10ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-04-014010.12775/QS.2025.40.59797The Role of Glutamine in Muscle Regeneration and Recovery: A Literature ReviewAneta Redner0https://orcid.org/0009-0006-1404-4305Julia Głowacz1https://orcid.org/0009-0000-3564-703XMichał Popiel2https://orcid.org/0009-0002-9726-6296Klaudia Kulig3https://orcid.org/0009-0003-1569-4180Maksymilian Wiśniowski4https://orcid.org/0009-0004-2470-3074Kamil Dziekoński5https://orcid.org/0009-0001-9958-1348Jakub Rybowski6https://orcid.org/0009-0002-6860-7805Patrycja Zwierzchlewska7https://orcid.org/0009-0005-8073-1042Kacper Buczek8https://orcid.org/0009-0005-0521-3536Hubert Gorycki9https://orcid.org/0009-0006-7497-2090Dominik Stanibuła10https://orcid.org/0009-0005-9409-6430Pure Clinic Krańcowa 77, 20-356 Lublin, PolandMedical University of Lublin Aleje Racławickie 1, 20-059 Lublin, PolandThe Little Prince Hospice of Lublin Lędzian 49, 20-828 Lublin, PolandMedical University of Lublin Aleje Racławickie 1, 20-059 Lublin, PolandMedical University of Lublin Aleje Racławickie 1, 20-059 Lublin, PolandCorten Dental Makolągwy 21, 02-811 Warsaw, PolandMedical University of Lublin Student Research Group at the Chair and Department of Oral Medicine Aleje Racławickie 1, 20-059 Lublin, PolandMedical University of Lublin Aleje Racławickie 1, 20-059 Lublin, PolandMedical University of Lublin Aleje Racławickie 1, 20-059 Lublin, PolandRobert Gorycki Gabinet Stomatologiczny ul. Płk. Stanisława Dąbka 2, 37-600 Lubaczów Medical University of Lublin Aleje Racławickie 1, 20-059 Lublin, Poland Purpose: The purpose of this review is to analise current scientific literature regarding the impact of glutamine supplementation on muscle repair, post-exercise recovery, and skeletal muscle preservation. It also examines the biological pathways through which glutamine may exert its effects, including modulation of inflammation and enhancement of protein turnover. Methodology: A review of scientific literature was performed, focusing on studies investigating the effects of glutamine supplementation on skeletal muscle recovery and function. The review includes experimental studies, clinical trials, and narrative reviews involving both athletic and clinical populations, with attention to various training conditions, health statuses, and supplementation strategies. Findings: The evidence indicates that glutamine can support recovery processes by mitigating muscle inflammation, improving redox balance, and promoting anabolic signalling. However, the degree of effectiveness varies, with more pronounced benefits observed in clinical and stress-related conditions compared to healthy individuals. The influence of dosage, supplementation timing, and individual variability remains a key consideration. Conclusions: Glutamine shows potential as a supportive agent in muscle regeneration, particularly in contexts of physical stress, illness, or injury. Further studies are needed to define its role in athletic, healthy populations and to optimize administration strategies based on individual needs and health status. https://apcz.umk.pl/QS/article/view/59797glutaminemuscle regenerationmuscle recoveryprotein metabolismoxidative stressamino acid supplementation |
| spellingShingle | Aneta Redner Julia Głowacz Michał Popiel Klaudia Kulig Maksymilian Wiśniowski Kamil Dziekoński Jakub Rybowski Patrycja Zwierzchlewska Kacper Buczek Hubert Gorycki Dominik Stanibuła The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review Quality in Sport glutamine muscle regeneration muscle recovery protein metabolism oxidative stress amino acid supplementation |
| title | The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review |
| title_full | The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review |
| title_fullStr | The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review |
| title_full_unstemmed | The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review |
| title_short | The Role of Glutamine in Muscle Regeneration and Recovery: A Literature Review |
| title_sort | role of glutamine in muscle regeneration and recovery a literature review |
| topic | glutamine muscle regeneration muscle recovery protein metabolism oxidative stress amino acid supplementation |
| url | https://apcz.umk.pl/QS/article/view/59797 |
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