Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia

We report a case of acute lymphoblastic leukemia that was complicated by neutropenic enterocolitis (typhlitis) during the initial period of remission-induction chemotherapy. The patient's clinical symptoms resolved after aggressive treatment with intravenous fluids and electrolytes, naso...

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Main Authors: Figen Ozçay, Sinan Mahir Kayiran, Namik Ozbek
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2003-07-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2897
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author Figen Ozçay
Sinan Mahir Kayiran
Namik Ozbek
author_facet Figen Ozçay
Sinan Mahir Kayiran
Namik Ozbek
author_sort Figen Ozçay
collection DOAJ
description We report a case of acute lymphoblastic leukemia that was complicated by neutropenic enterocolitis (typhlitis) during the initial period of remission-induction chemotherapy. The patient's clinical symptoms resolved after aggressive treatment with intravenous fluids and electrolytes, nasogastric decompression, bowel rest, total parenteral nutrition, broad-spectrum antibiotics, and granulocyte colony-stimulating factor. Netropenic enterocolitis should always be considered in neutropenic leukemic children with the triad of fever, vomiting, and abdominal pain. Gastrointestinal hemorrhage may also accompany the symptoms described above. Plain roentgenogram, ultrasonography and computed tomography of the abdomen are helpful for making the diagnosis of this clinical condition. Early recognition and proper medical management of neutropenic enterocolitis may prevent the need for surgical intervention, and/or be life-saving.
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publishDate 2003-07-01
publisher Hacettepe University Institute of Child Health
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series The Turkish Journal of Pediatrics
spelling doaj-art-bea70b3419d543e59f840ce75b92adc82025-08-20T02:55:39ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212003-07-01453Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemiaFigen Ozçay0Sinan Mahir KayiranNamik OzbekDepartment of Pediatrics, Başkent University Faculty of Medicine, Ankara, Turkey. We report a case of acute lymphoblastic leukemia that was complicated by neutropenic enterocolitis (typhlitis) during the initial period of remission-induction chemotherapy. The patient's clinical symptoms resolved after aggressive treatment with intravenous fluids and electrolytes, nasogastric decompression, bowel rest, total parenteral nutrition, broad-spectrum antibiotics, and granulocyte colony-stimulating factor. Netropenic enterocolitis should always be considered in neutropenic leukemic children with the triad of fever, vomiting, and abdominal pain. Gastrointestinal hemorrhage may also accompany the symptoms described above. Plain roentgenogram, ultrasonography and computed tomography of the abdomen are helpful for making the diagnosis of this clinical condition. Early recognition and proper medical management of neutropenic enterocolitis may prevent the need for surgical intervention, and/or be life-saving. https://turkjpediatr.org/article/view/2897
spellingShingle Figen Ozçay
Sinan Mahir Kayiran
Namik Ozbek
Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia
The Turkish Journal of Pediatrics
title Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia
title_full Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia
title_fullStr Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia
title_full_unstemmed Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia
title_short Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia
title_sort successful medical management of neutropenic enterocolitis typhlitis in a child with acute lymphoblastic leukemia
url https://turkjpediatr.org/article/view/2897
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AT sinanmahirkayiran successfulmedicalmanagementofneutropenicenterocolitistyphlitisinachildwithacutelymphoblasticleukemia
AT namikozbek successfulmedicalmanagementofneutropenicenterocolitistyphlitisinachildwithacutelymphoblasticleukemia