Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq
Background: The risk of blood-borne infections, particularly hepatitis B virus (HBV) and hepatitis C virus (HCV), continues to persist in developing countries among patients who receive blood products, such as hemophiliacs, but there is a lack of up-to-date data in such countries. This study aims to...
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Elsevier
2025-02-01
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| Series: | Journal of Clinical Virology Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S266703802500002X |
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| author | Salih A. Hama |
| author_facet | Salih A. Hama |
| author_sort | Salih A. Hama |
| collection | DOAJ |
| description | Background: The risk of blood-borne infections, particularly hepatitis B virus (HBV) and hepatitis C virus (HCV), continues to persist in developing countries among patients who receive blood products, such as hemophiliacs, but there is a lack of up-to-date data in such countries. This study aims to determine the prevalence of HBV and HCV infections among a group of hemophilia patients in Kurdistan Region, Iraq. Methods: This prospective cross-sectional study, conducted from June to September 2022, screened 117 hemophilic patients in the region for Hepatitis B surface antigen (HBsAg) and anti-HCV antibodies using serologic assays. Results: One hundred fifteen participants were male (98.3 %) with a mean age of 20.7 years (8–47). HBV seropositivity was found in 9 (7.7 %) patients, while HCV seropositivity was noted in 15 (12.8 %). No significant correlation was observed between HBV/HCV infectivity status and age, residency, or education status (p < 0.05). The prevalence of only HBV was significantly higher among patients with more frequent clotting factor intake (p = 0.016), which was associated with lower odds of HBV positivity (OR = 0.034, 95 % CI: 0.002–0.492). Moreover, HCV seropositive patients were more commonly associated with surgical history compared to negative cases (20 %vs. 3.9 %; p = 0.044), which was associated with significantly increased odds of HCV positivity (OR = 6.125, 95 % CI: 1.221–30.719). Conclusion: This study reveals an intermediate prevalence of HBV (7.7 %) and a high prevalence of HCV (12.8 %) infections among hemophilia patients in the Kurdistan Region, Iraq. |
| format | Article |
| id | doaj-art-bea655c0c1f045189e0e143334fec526 |
| institution | Kabale University |
| issn | 2667-0380 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical Virology Plus |
| spelling | doaj-art-bea655c0c1f045189e0e143334fec5262025-02-08T05:01:33ZengElsevierJournal of Clinical Virology Plus2667-03802025-02-0151100203Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, IraqSalih A. Hama0Biology Department, College of Science, University of Sulaimani, Kurdistan Region, Iraq; Medical Laboratory Science Department, College of Health Sciences, University of Human Development, Sulaymaniyah, Kurdistan Region, Iraq; Corresponding author at: Hawari Zanko, B91, Sulaimani, Kurdistan, IraqBackground: The risk of blood-borne infections, particularly hepatitis B virus (HBV) and hepatitis C virus (HCV), continues to persist in developing countries among patients who receive blood products, such as hemophiliacs, but there is a lack of up-to-date data in such countries. This study aims to determine the prevalence of HBV and HCV infections among a group of hemophilia patients in Kurdistan Region, Iraq. Methods: This prospective cross-sectional study, conducted from June to September 2022, screened 117 hemophilic patients in the region for Hepatitis B surface antigen (HBsAg) and anti-HCV antibodies using serologic assays. Results: One hundred fifteen participants were male (98.3 %) with a mean age of 20.7 years (8–47). HBV seropositivity was found in 9 (7.7 %) patients, while HCV seropositivity was noted in 15 (12.8 %). No significant correlation was observed between HBV/HCV infectivity status and age, residency, or education status (p < 0.05). The prevalence of only HBV was significantly higher among patients with more frequent clotting factor intake (p = 0.016), which was associated with lower odds of HBV positivity (OR = 0.034, 95 % CI: 0.002–0.492). Moreover, HCV seropositive patients were more commonly associated with surgical history compared to negative cases (20 %vs. 3.9 %; p = 0.044), which was associated with significantly increased odds of HCV positivity (OR = 6.125, 95 % CI: 1.221–30.719). Conclusion: This study reveals an intermediate prevalence of HBV (7.7 %) and a high prevalence of HCV (12.8 %) infections among hemophilia patients in the Kurdistan Region, Iraq.http://www.sciencedirect.com/science/article/pii/S266703802500002XBleeding disorderHemophiliaHepatitis BHepatitis C |
| spellingShingle | Salih A. Hama Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq Journal of Clinical Virology Plus Bleeding disorder Hemophilia Hepatitis B Hepatitis C |
| title | Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq |
| title_full | Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq |
| title_fullStr | Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq |
| title_full_unstemmed | Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq |
| title_short | Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq |
| title_sort | seroprevalence of hepatitis b and c virus among a group of hemophilia patients in kurdistan region iraq |
| topic | Bleeding disorder Hemophilia Hepatitis B Hepatitis C |
| url | http://www.sciencedirect.com/science/article/pii/S266703802500002X |
| work_keys_str_mv | AT salihahama seroprevalenceofhepatitisbandcvirusamongagroupofhemophiliapatientsinkurdistanregioniraq |