A recombinant BCG with surface-displayed antigen induces humoral and cellular immune responses

A recombinant BCG with surface-displayed antigen induces humoral and cellular immune responses

Abstract Bacillus Calmette-Guérin (BCG) is an attenuated vaccine widely used for tuberculosis prevention. While BCG has long been perceived as an intracellular candidate vector for delivering antigens against infectious diseases and cancers, challenges persist in inducing durable immune responses, p...

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Bibliographic Details
Main Authors: Jin-Yu Zhang, Zhi-Dong Hu, Li-Xiao Xing, Zhen-Yan Chen, Jin-Chuan Xu, Qiao-Yu Wu, Juan Wu, Guo-Ping Zhao, Xiao-Yong Fan, Liang-Dong Lyu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-00553-x
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