Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients

This study was aimed to evaluate the concentration of serum vitamin D, potassium, D-dimer, and lactate dehydrogenase (LDH) among coronavirus patients and control healthy individual according to their age ranges. The present study weel-done in AL-Zahra teaching hospital, Wasit province, Iraq; from S...

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Main Author: Aqdas Mohammed Sfaieh
Format: Article
Language:English
Published: College of Education for Pure Sciences 2024-12-01
Series:Wasit Journal for Pure Sciences
Online Access:https://wjps.uowasit.edu.iq/index.php/wjps/article/view/589
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author Aqdas Mohammed Sfaieh
author_facet Aqdas Mohammed Sfaieh
author_sort Aqdas Mohammed Sfaieh
collection DOAJ
description This study was aimed to evaluate the concentration of serum vitamin D, potassium, D-dimer, and lactate dehydrogenase (LDH) among coronavirus patients and control healthy individual according to their age ranges. The present study weel-done in AL-Zahra teaching hospital, Wasit province, Iraq; from September 2022 to February, 2023, the role of this study included 80 patients; 40 males (50.00 %) and 40 females (50.00 %) with age range (21-80 year). While, the samples of control groups consist of 60 healthy individuals, 30 males (50.00%) and 30 females (50.00%) with same age of patients group. Both study groups were separated into three age ranges; The 1st age range (21-40) year, 2nd age range (41-60) year, and the 3rd age range (61-80) year, each group of (patients and healthy subject) were separated into two subgroups (male and female).  The present study recorded that the concentrations of serum vitamin D and potassium significantly decreased (p≤0.05) among (male and female) coronavirus patients as compared with control volunteers in all age ranges. In contrast, serum D-dimer and LDH were elevated significantly (p≤0.05) among male and female of patient’s groups in the 2nd and 3rd age range (41-60 and 61-80) year, while non- significant variation was recorded in the 1st age range (21-40) year in compression to control subject. Conclusion: Current study concluded that there were clearly significant association between vitamin- D insufficiency and coronavirus susceptibility. Thus, taking a vitamin D supplement can help to reduce the complication of coronavirus infection. Also, significant decreased in serum potassium levels considered as a risk of severe progression of acute cardiac failure among coronavirus patients. While, significant increased in serum D-dimer, and LDH may be associated with increased severity and mortality among coronavirus patients.
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spelling doaj-art-be9d52d3018d46daa8e77f4ec84b26592025-08-20T02:10:41ZengCollege of Education for Pure SciencesWasit Journal for Pure Sciences2790-52332790-52412024-12-013410.31185/wjps.589Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus PatientsAqdas Mohammed Sfaieh 0Department of Pathological Analysis, College of Science, University of Wasit, Wasit, IRAQ. This study was aimed to evaluate the concentration of serum vitamin D, potassium, D-dimer, and lactate dehydrogenase (LDH) among coronavirus patients and control healthy individual according to their age ranges. The present study weel-done in AL-Zahra teaching hospital, Wasit province, Iraq; from September 2022 to February, 2023, the role of this study included 80 patients; 40 males (50.00 %) and 40 females (50.00 %) with age range (21-80 year). While, the samples of control groups consist of 60 healthy individuals, 30 males (50.00%) and 30 females (50.00%) with same age of patients group. Both study groups were separated into three age ranges; The 1st age range (21-40) year, 2nd age range (41-60) year, and the 3rd age range (61-80) year, each group of (patients and healthy subject) were separated into two subgroups (male and female).  The present study recorded that the concentrations of serum vitamin D and potassium significantly decreased (p≤0.05) among (male and female) coronavirus patients as compared with control volunteers in all age ranges. In contrast, serum D-dimer and LDH were elevated significantly (p≤0.05) among male and female of patient’s groups in the 2nd and 3rd age range (41-60 and 61-80) year, while non- significant variation was recorded in the 1st age range (21-40) year in compression to control subject. Conclusion: Current study concluded that there were clearly significant association between vitamin- D insufficiency and coronavirus susceptibility. Thus, taking a vitamin D supplement can help to reduce the complication of coronavirus infection. Also, significant decreased in serum potassium levels considered as a risk of severe progression of acute cardiac failure among coronavirus patients. While, significant increased in serum D-dimer, and LDH may be associated with increased severity and mortality among coronavirus patients. https://wjps.uowasit.edu.iq/index.php/wjps/article/view/589
spellingShingle Aqdas Mohammed Sfaieh
Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients
Wasit Journal for Pure Sciences
title Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients
title_full Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients
title_fullStr Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients
title_full_unstemmed Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients
title_short Physiological Disturbances of Vitamin D and some Biochemical Parameters for Coronavirus Patients
title_sort physiological disturbances of vitamin d and some biochemical parameters for coronavirus patients
url https://wjps.uowasit.edu.iq/index.php/wjps/article/view/589
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