Combined effects of physical activity, cognitive activity, and dietary patterns on cognitive impairment in older adults with consideration of APOE genotype: a cohort study

Combined effects of physical activity, cognitive activity, and dietary patterns on cognitive impairment in older adults with consideration of APOE genotype: a cohort study

Abstract Background This study aims to evaluate the combination effects of physical activity (PA), cognitive activity (CA), and dietary patterns impacts cognitive impairment among older adults, and whether these associations differ by apolipoprotein E (APOE) genotype. Methods A total of 18,909 adult...

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Main Authors: Wen-Fang Zhong, Xiao-Meng Wang, Huan Chen, Wei-Qi Song, Jian Gao, Pei-Liang Chen, Qiao-Qiao Shen, Fang-Fei You, Chuan Li, Yue-Bin Lv, Zhi-Hao Li, Xiao-Ming Shi, Chen Mao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Healthy eating index
Physical activity
Cognitive activity
Older Chinese adult
Cohort study
Online Access:https://doi.org/10.1186/s13195-025-01806-7
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