Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature

Background. Kikuchi–Fujimoto disease (KFD) is a rare, benign, and self-limiting disease that is commonly associated with cervical lymphadenopathy and fever. The disease has a wide spectrum of clinical manifestations, and definitive diagnosis is based on the histological appearance in the excision bi...

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Main Authors: Karo Servatyari, Hero Yazdanpanah, Chamara Dalugama
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2020/9785104
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author Karo Servatyari
Hero Yazdanpanah
Chamara Dalugama
author_facet Karo Servatyari
Hero Yazdanpanah
Chamara Dalugama
author_sort Karo Servatyari
collection DOAJ
description Background. Kikuchi–Fujimoto disease (KFD) is a rare, benign, and self-limiting disease that is commonly associated with cervical lymphadenopathy and fever. The disease has a wide spectrum of clinical manifestations, and definitive diagnosis is based on the histological appearance in the excision biopsy of the lymph nodes. Recurrence of KFD is reported rarely. Case Presentation. A 56-year-old Iranian woman with a background history of thrombocytopenia presented with fever, malaise, loss of appetite, and weight loss with cervical lymphadenopathy. The excision biopsy of the cervical lymph nodes confirmed the diagnosis of KFD, and she made a full recovery with improvement of symptoms, regression of cervical lymph nodes, and normalization inflammatory markers. One year after remission, she presented with similar clinico-biochemical profile, and repeat biopsy confirmed KFD. Conclusion. Although the rate of recurrence of the disease is very low, the treating physician should consider the possibility and confirm it histologically.
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spelling doaj-art-be8f89a2f62d4d06b6ab63954b1aebd42025-02-03T06:46:55ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/97851049785104Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing NatureKaro Servatyari0Hero Yazdanpanah1Chamara Dalugama2Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, IranStudent Research Committee, Kurdistan University of Medical Sciences, Sanandaj, IranLecturer in Medicine, Department of Medicine, University of Peradeniya, Peradeniya, Sri LankaBackground. Kikuchi–Fujimoto disease (KFD) is a rare, benign, and self-limiting disease that is commonly associated with cervical lymphadenopathy and fever. The disease has a wide spectrum of clinical manifestations, and definitive diagnosis is based on the histological appearance in the excision biopsy of the lymph nodes. Recurrence of KFD is reported rarely. Case Presentation. A 56-year-old Iranian woman with a background history of thrombocytopenia presented with fever, malaise, loss of appetite, and weight loss with cervical lymphadenopathy. The excision biopsy of the cervical lymph nodes confirmed the diagnosis of KFD, and she made a full recovery with improvement of symptoms, regression of cervical lymph nodes, and normalization inflammatory markers. One year after remission, she presented with similar clinico-biochemical profile, and repeat biopsy confirmed KFD. Conclusion. Although the rate of recurrence of the disease is very low, the treating physician should consider the possibility and confirm it histologically.http://dx.doi.org/10.1155/2020/9785104
spellingShingle Karo Servatyari
Hero Yazdanpanah
Chamara Dalugama
Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature
Case Reports in Medicine
title Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature
title_full Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature
title_fullStr Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature
title_full_unstemmed Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature
title_short Rare Presentation of Self-Limiting Kikuchi–Fujimoto Disease in Relapsing Nature
title_sort rare presentation of self limiting kikuchi fujimoto disease in relapsing nature
url http://dx.doi.org/10.1155/2020/9785104
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