Marked mucosal lipid shifts in treatment refractory inflammatory bowel disease: a lipidomic study

Marked mucosal lipid shifts in treatment refractory inflammatory bowel disease: a lipidomic study

Abstract Background Mechanisms causing non-response to biological agents in IBD remain to be fully understood. Thus, we aimed to characterize the lipid profile in treatment refractory non-immunogenic patients with adequate trough-levels. Methods Patients with IBD refractory to treatment with anti-tu...

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Bibliographic Details
Main Authors: Øystein K. Moe, Qian Gao, Dawei Geng, Einar Jensen, Rasmus Goll, Oddmund Nestegard, Mona D. Gundersen, Jon R. Florholmen, T. Moritz
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Gastroenterology
Subjects:
Biological therapy
Inflammatory bowel disease
Non-response
Lipids
Online Access:https://doi.org/10.1186/s12876-025-03944-6
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