Effect of sibutramine on intraocular pressure
Objective: This study evaluated the effects of sibutramine on intraocular pressure (IOP) and body-mass index (BMI). Methods: Thirty obese females (body-mass index >30 kg/m2) treated with sibutramine (10 mg/day) plus diet restriction for 3 months were included in the study. IOP, BMI, and blood...
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| Format: | Article |
| Language: | English |
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Philippine Academy of Ophthalmology
2006-06-01
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| Series: | Philippine Journal of Ophthalmology |
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| Online Access: | https://paojournal.com/index.php/pjo/article/view/369 |
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| author | Ahmet Satici, MD Nevin Yilmaz, MD Mustafa Guzey, MD Adil Kilic, MD |
| author_facet | Ahmet Satici, MD Nevin Yilmaz, MD Mustafa Guzey, MD Adil Kilic, MD |
| author_sort | Ahmet Satici, MD |
| collection | DOAJ |
| description | Objective: This study evaluated the effects of sibutramine on intraocular pressure (IOP) and body-mass index (BMI).
Methods: Thirty obese females (body-mass index >30 kg/m2) treated with sibutramine (10 mg/day) plus diet restriction for 3 months were included in the study. IOP, BMI, and blood biochemical parameters were measured at the beginning and end of the treatment. Results were evaluated statistically by paired t-test, analysis of variance, and least-significant difference test.
Results: A statistically significant decrease was observed in the mean body-mass index (p < 0.001) and serum triglyceride (p < 0.001), while a statistically insignificant increase was observed in IOP (p = 0.54).
Conclusion: While sibutramine provided an effective means for weight loss, it caused a slight increase in IOP, although this was not statistically significant. Nevertheless, it is prudent to monitor IOP in selected obese patients treated with sibutramine. |
| format | Article |
| id | doaj-art-be8914aea2e14e4782fc6db737fda605 |
| institution | Kabale University |
| issn | 0031-7659 |
| language | English |
| publishDate | 2006-06-01 |
| publisher | Philippine Academy of Ophthalmology |
| record_format | Article |
| series | Philippine Journal of Ophthalmology |
| spelling | doaj-art-be8914aea2e14e4782fc6db737fda6052025-08-20T03:40:54ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592006-06-013113537369Effect of sibutramine on intraocular pressureAhmet Satici, MD0Nevin Yilmaz, MD1Mustafa Guzey, MD2Adil Kilic, MD3Department of OphthalmologyDepartment of Internal Medicine Harran University Sanliurfa, TurkeyDepartment of Ophthalmology Department of OphthalmologyObjective: This study evaluated the effects of sibutramine on intraocular pressure (IOP) and body-mass index (BMI). Methods: Thirty obese females (body-mass index >30 kg/m2) treated with sibutramine (10 mg/day) plus diet restriction for 3 months were included in the study. IOP, BMI, and blood biochemical parameters were measured at the beginning and end of the treatment. Results were evaluated statistically by paired t-test, analysis of variance, and least-significant difference test. Results: A statistically significant decrease was observed in the mean body-mass index (p < 0.001) and serum triglyceride (p < 0.001), while a statistically insignificant increase was observed in IOP (p = 0.54). Conclusion: While sibutramine provided an effective means for weight loss, it caused a slight increase in IOP, although this was not statistically significant. Nevertheless, it is prudent to monitor IOP in selected obese patients treated with sibutramine.https://paojournal.com/index.php/pjo/article/view/369intraocular pressureobesitysibutramine |
| spellingShingle | Ahmet Satici, MD Nevin Yilmaz, MD Mustafa Guzey, MD Adil Kilic, MD Effect of sibutramine on intraocular pressure Philippine Journal of Ophthalmology intraocular pressure obesity sibutramine |
| title | Effect of sibutramine on intraocular pressure |
| title_full | Effect of sibutramine on intraocular pressure |
| title_fullStr | Effect of sibutramine on intraocular pressure |
| title_full_unstemmed | Effect of sibutramine on intraocular pressure |
| title_short | Effect of sibutramine on intraocular pressure |
| title_sort | effect of sibutramine on intraocular pressure |
| topic | intraocular pressure obesity sibutramine |
| url | https://paojournal.com/index.php/pjo/article/view/369 |
| work_keys_str_mv | AT ahmetsaticimd effectofsibutramineonintraocularpressure AT nevinyilmazmd effectofsibutramineonintraocularpressure AT mustafaguzeymd effectofsibutramineonintraocularpressure AT adilkilicmd effectofsibutramineonintraocularpressure |