Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.

<h4>Introduction</h4>Antimicrobial resistance (AMR) constitutes a significant threat to global health and food security, typically associated with high morbidity and mortality rate. The high burden of infectious diseases coupled with the weak health systems in most countries of Africa ma...

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Main Authors: Chinwe Juliana Iwu-Jaja, Anelisa Jaca, Ishmael Festus Jaja, Portia Jordan, Phelele Bhengu, Chidozie Declan Iwu, Joseph Okeibunor, Humphrey Karamagi, Prosper Tumusiime, Walter Fuller, Ali Ahmed Yahaya, Charles Wiysonge, Laetitia Gahimbare
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254737&type=printable
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author Chinwe Juliana Iwu-Jaja
Anelisa Jaca
Ishmael Festus Jaja
Portia Jordan
Phelele Bhengu
Chidozie Declan Iwu
Joseph Okeibunor
Humphrey Karamagi
Prosper Tumusiime
Walter Fuller
Ali Ahmed Yahaya
Charles Wiysonge
Laetitia Gahimbare
author_facet Chinwe Juliana Iwu-Jaja
Anelisa Jaca
Ishmael Festus Jaja
Portia Jordan
Phelele Bhengu
Chidozie Declan Iwu
Joseph Okeibunor
Humphrey Karamagi
Prosper Tumusiime
Walter Fuller
Ali Ahmed Yahaya
Charles Wiysonge
Laetitia Gahimbare
author_sort Chinwe Juliana Iwu-Jaja
collection DOAJ
description <h4>Introduction</h4>Antimicrobial resistance (AMR) constitutes a significant threat to global health and food security, typically associated with high morbidity and mortality rate. The high burden of infectious diseases coupled with the weak health systems in most countries of Africa magnifies the risk of increasing AMR and its consequences thereof. This scoping review will be aimed at mapping the evidence on interventions used to prevent and manage antimicrobial resistance in Africa, guided by the "One Health" concept.<h4>Methods</h4>We will consider interventions targeting multiple sectors such as health care systems, the agricultural and veterinary sectors. The outcomes to be considered include reduction of AMR decreased morbidity and mortality due to infectious diseases, increased awareness for rational use of antimicrobials and reduced antibiotic consumption. We will include all types of studies regardless of study designs conducted within the context of the WHO African region. Studies will be excluded if they are not conducted in Africa and if they are literature reviews, only describing the concept of AMR without mentioning interventions. We will include studies identified through a comprehensive search of peer-reviewed and grey literature databases. In addition, we will search the reference lists of included studies and relevant reviews. Finally, we plan to do a citation search for included studies. Findings of this review will be narratively synthesized.
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institution Kabale University
issn 1932-6203
language English
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publisher Public Library of Science (PLoS)
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spelling doaj-art-be804ed08e6442a38bec5ac0696e1b392025-02-05T05:32:57ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01167e025473710.1371/journal.pone.0254737Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.Chinwe Juliana Iwu-JajaAnelisa JacaIshmael Festus JajaPortia JordanPhelele BhenguChidozie Declan IwuJoseph OkeibunorHumphrey KaramagiProsper TumusiimeWalter FullerAli Ahmed YahayaCharles WiysongeLaetitia Gahimbare<h4>Introduction</h4>Antimicrobial resistance (AMR) constitutes a significant threat to global health and food security, typically associated with high morbidity and mortality rate. The high burden of infectious diseases coupled with the weak health systems in most countries of Africa magnifies the risk of increasing AMR and its consequences thereof. This scoping review will be aimed at mapping the evidence on interventions used to prevent and manage antimicrobial resistance in Africa, guided by the "One Health" concept.<h4>Methods</h4>We will consider interventions targeting multiple sectors such as health care systems, the agricultural and veterinary sectors. The outcomes to be considered include reduction of AMR decreased morbidity and mortality due to infectious diseases, increased awareness for rational use of antimicrobials and reduced antibiotic consumption. We will include all types of studies regardless of study designs conducted within the context of the WHO African region. Studies will be excluded if they are not conducted in Africa and if they are literature reviews, only describing the concept of AMR without mentioning interventions. We will include studies identified through a comprehensive search of peer-reviewed and grey literature databases. In addition, we will search the reference lists of included studies and relevant reviews. Finally, we plan to do a citation search for included studies. Findings of this review will be narratively synthesized.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254737&type=printable
spellingShingle Chinwe Juliana Iwu-Jaja
Anelisa Jaca
Ishmael Festus Jaja
Portia Jordan
Phelele Bhengu
Chidozie Declan Iwu
Joseph Okeibunor
Humphrey Karamagi
Prosper Tumusiime
Walter Fuller
Ali Ahmed Yahaya
Charles Wiysonge
Laetitia Gahimbare
Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.
PLoS ONE
title Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.
title_full Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.
title_fullStr Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.
title_full_unstemmed Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.
title_short Preventing and managing antimicrobial resistance in the African region: A scoping review protocol.
title_sort preventing and managing antimicrobial resistance in the african region a scoping review protocol
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254737&type=printable
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