Exploring the differential functions of circulating follicular helper T and peripheral helper T cells in rheumatoid arthritis based on metabolism patterns

Exploring the differential functions of circulating follicular helper T and peripheral helper T cells in rheumatoid arthritis based on metabolism patterns

IntroductionThe number of circulating follicular helper T (cTfh) and peripheral helper T (Tph) cells is elevated in rheumatoid arthritis (RA), yet the molecular mechanisms mediating their specific contributions to RA pathology remain unclear. In this study, we explored the distinct function of cTfh...

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Bibliographic Details
Main Authors: Ziran Bai, Siwen Yang, Jinyi Ren, Cheng Zhang, Xianmei Chen, Huina Huang, Guan Wang, Yawei Tang, Jingjing Qi, Xia Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
Tfh cells
Tph cells
glycolysis
mtROS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608675/full
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