Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study

Objectives: The aim of this article is to evaluate and compare the efficacy of subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis. Materials and Methods: One hundred and twenty patients with c...

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Main Authors: Koushik Mukherjee, BJ Janardhana Amaranath, Neelam Das, Anishka Dhanai, Kumari Pallavi, Priya Katiyar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_738_24
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author Koushik Mukherjee
BJ Janardhana Amaranath
Neelam Das
Anishka Dhanai
Kumari Pallavi
Priya Katiyar
author_facet Koushik Mukherjee
BJ Janardhana Amaranath
Neelam Das
Anishka Dhanai
Kumari Pallavi
Priya Katiyar
author_sort Koushik Mukherjee
collection DOAJ
description Objectives: The aim of this article is to evaluate and compare the efficacy of subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis. Materials and Methods: One hundred and twenty patients with chronic periodontitis were included in this study and assigned into three groups. In Group I, Group II, and Group III, SRP was done followed by subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel in Group I, II, and III, respectively, at baseline 7, 14, and 21 days. Recordings of clinical parameters (gingival index [GI], probing pocket depth [PPD], clinical attachment level [CAL]) were done at baseline and one month. Results: The mean GI, PPD, and CAL scores at baseline for Group I was 2.78 ± 0.42, 2.78 ± 0.42, and 2.66 ± 0.38; for Group II was 2.64 ± 0.39, 6.40 ± 0.50, and 6.40 ± 0.50; and for Group III was 6.00 ± 0.00, 6.40 ± 0.50, and 6.40 ± 0.50, and the scores after one month for Group I was 1.10 ± 0.38, 0.21 ± 0.07, and 0.07 ± 0.05; for Group II was 0.05 ± 0.05, 5.40 ± 0.50, and 5.75 ± 0.44; and for Group III was 5.00 ± 0.00, 5.75 ± 0.44, and 5.28 ± 0.45, with the level of significance being (P < 0.001). Conclusion: The ozonated olive oil and chlorhexidine gel have shown significant improvement in periodontal health compared to plain olive oil. Ozonated olive oil can be used as local drug delivery (LDD), an adjunct to SRP in chronic periodontitis which is safe and well accepted by patients without any noticeable side effects.
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institution Kabale University
issn 0976-4879
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publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-be78c9b4752e42e394159fc4d8bc13d12025-01-12T14:19:53ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3332S333410.4103/jpbs.jpbs_738_24Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical StudyKoushik MukherjeeBJ Janardhana AmaranathNeelam DasAnishka DhanaiKumari PallaviPriya KatiyarObjectives: The aim of this article is to evaluate and compare the efficacy of subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis. Materials and Methods: One hundred and twenty patients with chronic periodontitis were included in this study and assigned into three groups. In Group I, Group II, and Group III, SRP was done followed by subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel in Group I, II, and III, respectively, at baseline 7, 14, and 21 days. Recordings of clinical parameters (gingival index [GI], probing pocket depth [PPD], clinical attachment level [CAL]) were done at baseline and one month. Results: The mean GI, PPD, and CAL scores at baseline for Group I was 2.78 ± 0.42, 2.78 ± 0.42, and 2.66 ± 0.38; for Group II was 2.64 ± 0.39, 6.40 ± 0.50, and 6.40 ± 0.50; and for Group III was 6.00 ± 0.00, 6.40 ± 0.50, and 6.40 ± 0.50, and the scores after one month for Group I was 1.10 ± 0.38, 0.21 ± 0.07, and 0.07 ± 0.05; for Group II was 0.05 ± 0.05, 5.40 ± 0.50, and 5.75 ± 0.44; and for Group III was 5.00 ± 0.00, 5.75 ± 0.44, and 5.28 ± 0.45, with the level of significance being (P < 0.001). Conclusion: The ozonated olive oil and chlorhexidine gel have shown significant improvement in periodontal health compared to plain olive oil. Ozonated olive oil can be used as local drug delivery (LDD), an adjunct to SRP in chronic periodontitis which is safe and well accepted by patients without any noticeable side effects.https://journals.lww.com/10.4103/jpbs.jpbs_738_24adjunctive therapychlorhexidinechronic periodontitislocal drug deliveryozonated olive oilplain olive oil
spellingShingle Koushik Mukherjee
BJ Janardhana Amaranath
Neelam Das
Anishka Dhanai
Kumari Pallavi
Priya Katiyar
Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study
Journal of Pharmacy and Bioallied Sciences
adjunctive therapy
chlorhexidine
chronic periodontitis
local drug delivery
ozonated olive oil
plain olive oil
title Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study
title_full Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study
title_fullStr Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study
title_full_unstemmed Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study
title_short Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study
title_sort efficacy of olive oil ozonated olive oil and chlorhexidine gel as an adjunct to scaling and root planing in chronic periodontitis a clinical study
topic adjunctive therapy
chlorhexidine
chronic periodontitis
local drug delivery
ozonated olive oil
plain olive oil
url https://journals.lww.com/10.4103/jpbs.jpbs_738_24
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