Breast cancer is detectable from peripheral blood using machine learning over T cell receptor repertoires
Abstract The immune system’s defense abilities rely on the diversity of T and B lymphocytes. T Cell Receptors (TCRs) are generated through V(D)J recombination, where distinct genetic elements combine and undergo modifications, creating extensive variability. In breast cancer, the most frequently dia...
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| Main Authors: | Miriam Zuckerbrot-Schuldenfrei, Ari Raphael, Alona Zilberberg, Sol Efroni |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00573-3 |
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