Breast cancer is detectable from peripheral blood using machine learning over T cell receptor repertoires

Abstract The immune system’s defense abilities rely on the diversity of T and B lymphocytes. T Cell Receptors (TCRs) are generated through V(D)J recombination, where distinct genetic elements combine and undergo modifications, creating extensive variability. In breast cancer, the most frequently dia...

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Bibliographic Details
Main Authors: Miriam Zuckerbrot-Schuldenfrei, Ari Raphael, Alona Zilberberg, Sol Efroni
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00573-3
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