Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change

Abstract. Background. Epimedii Folium is well known for its medicinal value. Four Epimedium species—Euphorbia brevicornu, E. sagittatum, E. pubescens, and E. koreanum—are the designated original plants of Epimedii Folium. Objective. The objective of this study is to facilitate the identification of...

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Main Authors: Yiheng Wang, Kangjia Liu, Meng Li, Yuran Bai, Chengcai Zhang, Binbin Yan, Wenpan Dong, Yan Zhang, Jiahui Sun
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2025-06-01
Series:Science of Traditional Chinese Medicine
Online Access:http://journals.lww.com/10.1097/st9.0000000000000066
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author Yiheng Wang
Kangjia Liu
Meng Li
Yuran Bai
Chengcai Zhang
Binbin Yan
Wenpan Dong
Yan Zhang
Jiahui Sun
author_facet Yiheng Wang
Kangjia Liu
Meng Li
Yuran Bai
Chengcai Zhang
Binbin Yan
Wenpan Dong
Yan Zhang
Jiahui Sun
author_sort Yiheng Wang
collection DOAJ
description Abstract. Background. Epimedii Folium is well known for its medicinal value. Four Epimedium species—Euphorbia brevicornu, E. sagittatum, E. pubescens, and E. koreanum—are the designated original plants of Epimedii Folium. Objective. The objective of this study is to facilitate the identification of the four Epimedium species and clarify their distributional responses to climate change. Methods. In this study, we assessed the genetic divergence of the four species and identified the molecular markers for species identification by using chloroplast genome sequences. Furthermore, we forecasted the distribution of potentially suitable regions of the four species Folium under climate change. Results. The authors obtained 26 chloroplast genome sequences of the four species and identified 1393 variable sites and 273 indel events. Genetic divergence analyses revealed that E. koreanum had long genetic distance from the other three species. Compared with the complete chloroplast genome, six hypervariable markers were discovered, and both rps4-trnL and ndhF were chosen as Epimedii Folium-specific DNA barcodes. Climate change is expected to influence the geographical distribution of the four Epimedium species, which were primarily found in China, South Korea, and Japan, leading to both expansion and contraction of their distribution ranges. Conclusion. Two identification markers were selected as the specific DNA barcodes for all four original plant species of Epimedii Folium. In addition, the shift of potential suitable area in various climate scenarios has been predicted. With the support of identification markers and the dynamics of suitable distribution areas, we are able to establish a foundation for the sustainable utilization of medicinal Epimedium resources in the future.
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institution Kabale University
issn 2836-922X
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language English
publishDate 2025-06-01
publisher Wolters Kluwer Health/LWW
record_format Article
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spelling doaj-art-be70f765b74c4b7585e80d999705ffbb2025-08-20T03:33:27ZengWolters Kluwer Health/LWWScience of Traditional Chinese Medicine2836-922X2836-92112025-06-013217818510.1097/st9.0000000000000066202506000-00008Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate changeYiheng Wang0Kangjia Liu1Meng Li2Yuran Bai3Chengcai Zhang4Binbin Yan5Wenpan Dong6Yan Zhang7Jiahui Sun8a State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, Chinac School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, Chinaa State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, Chinac School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, Chinaa State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, Chinaa State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, Chinac School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, Chinaa State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, Chinaa State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, ChinaAbstract. Background. Epimedii Folium is well known for its medicinal value. Four Epimedium species—Euphorbia brevicornu, E. sagittatum, E. pubescens, and E. koreanum—are the designated original plants of Epimedii Folium. Objective. The objective of this study is to facilitate the identification of the four Epimedium species and clarify their distributional responses to climate change. Methods. In this study, we assessed the genetic divergence of the four species and identified the molecular markers for species identification by using chloroplast genome sequences. Furthermore, we forecasted the distribution of potentially suitable regions of the four species Folium under climate change. Results. The authors obtained 26 chloroplast genome sequences of the four species and identified 1393 variable sites and 273 indel events. Genetic divergence analyses revealed that E. koreanum had long genetic distance from the other three species. Compared with the complete chloroplast genome, six hypervariable markers were discovered, and both rps4-trnL and ndhF were chosen as Epimedii Folium-specific DNA barcodes. Climate change is expected to influence the geographical distribution of the four Epimedium species, which were primarily found in China, South Korea, and Japan, leading to both expansion and contraction of their distribution ranges. Conclusion. Two identification markers were selected as the specific DNA barcodes for all four original plant species of Epimedii Folium. In addition, the shift of potential suitable area in various climate scenarios has been predicted. With the support of identification markers and the dynamics of suitable distribution areas, we are able to establish a foundation for the sustainable utilization of medicinal Epimedium resources in the future.http://journals.lww.com/10.1097/st9.0000000000000066
spellingShingle Yiheng Wang
Kangjia Liu
Meng Li
Yuran Bai
Chengcai Zhang
Binbin Yan
Wenpan Dong
Yan Zhang
Jiahui Sun
Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change
Science of Traditional Chinese Medicine
title Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change
title_full Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change
title_fullStr Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change
title_full_unstemmed Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change
title_short Original species identification of Epimedii Folium (Epimedium) and their distributional responses to climate change
title_sort original species identification of epimedii folium epimedium and their distributional responses to climate change
url http://journals.lww.com/10.1097/st9.0000000000000066
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