B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis

Purpose. To report B-scan and “En-face” spectral-domain optical coherence tomography (SD-OCT) findings in acute retinal pigment epitheliitis (ARPE). Methods. Two patients (3 eyes) with ARPE were examined. Fluorescein and indocyanine green (ICGA) angiography, B-scan, and “En-face” SD-OCT were perfor...

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Main Authors: Flore De Bats, Benjamin Wolff, Martine Mauget-Faÿsse, Claire Scemama, Laurent Kodjikian
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/260237
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author Flore De Bats
Benjamin Wolff
Martine Mauget-Faÿsse
Claire Scemama
Laurent Kodjikian
author_facet Flore De Bats
Benjamin Wolff
Martine Mauget-Faÿsse
Claire Scemama
Laurent Kodjikian
author_sort Flore De Bats
collection DOAJ
description Purpose. To report B-scan and “En-face” spectral-domain optical coherence tomography (SD-OCT) findings in acute retinal pigment epitheliitis (ARPE). Methods. Two patients (3 eyes) with ARPE were examined. Fluorescein and indocyanine green (ICGA) angiography, B-scan, and “En-face” SD-OCT were performed in each patient at initial and follow-up visits. Results. Both patients presented with acute onset of blurred vision, and one with bilateral involvement. B-can OCT revealed disruption of the macular retinal pigment epithelial (RPE) inner band layer and photoreceptors’ inner and outer segment (IS-OS) junction. Hyperreflective dots were observed in the outer nuclear layer (ONL) above the RPE/IS-OS disruption. Just around these hyperreflective dots, slight thickening of the hyperreflective IS/OS junction was observed. During the late phase, indocyanine green angiography (ICGA) showed a macular cockade-like hyperfluorescent halo. “En-face” OCT showed the same cockade-like appearance with a hyporeflective center and a hyperreflective border matching the pattern observed on ICGA. At followup, as vision improved without treatment, B-scan OCT demonstrated progressive resolution of the hyperreflective and disrupted lesions; “en-face” OCT also showed disappearance of the macular cockade-like halo with a transient discrete hyperreflective macular star at the RPE level in one eye. Conclusion. “En-face” OCT associated with B-scan SD-OCT analysis appears to be very helpful in the diagnosis and followup of ARPE. The pathophysiology of ARPE remains complex and still poorly understood. These techniques help define the location and extent of structural damage occurring in this disease.
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spelling doaj-art-be5a8d60aa644f15b5035b26f998af7e2025-08-20T03:22:59ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/260237260237B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment EpitheliitisFlore De Bats0Benjamin Wolff1Martine Mauget-Faÿsse2Claire Scemama3Laurent Kodjikian4Department of Ophthalmology Croix-Rousse University Hospital and Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande Rue de la Croix-Rousse, 69317 Lyon Cedex 04, FranceSahel Department, Rothschild Ophthalmologic Foundation, 25 Rue Manin, 75019 Paris, FranceSahel Department, Rothschild Ophthalmologic Foundation, 25 Rue Manin, 75019 Paris, FranceSahel Department, Rothschild Ophthalmologic Foundation, 25 Rue Manin, 75019 Paris, FranceDepartment of Ophthalmology Croix-Rousse University Hospital and Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande Rue de la Croix-Rousse, 69317 Lyon Cedex 04, FrancePurpose. To report B-scan and “En-face” spectral-domain optical coherence tomography (SD-OCT) findings in acute retinal pigment epitheliitis (ARPE). Methods. Two patients (3 eyes) with ARPE were examined. Fluorescein and indocyanine green (ICGA) angiography, B-scan, and “En-face” SD-OCT were performed in each patient at initial and follow-up visits. Results. Both patients presented with acute onset of blurred vision, and one with bilateral involvement. B-can OCT revealed disruption of the macular retinal pigment epithelial (RPE) inner band layer and photoreceptors’ inner and outer segment (IS-OS) junction. Hyperreflective dots were observed in the outer nuclear layer (ONL) above the RPE/IS-OS disruption. Just around these hyperreflective dots, slight thickening of the hyperreflective IS/OS junction was observed. During the late phase, indocyanine green angiography (ICGA) showed a macular cockade-like hyperfluorescent halo. “En-face” OCT showed the same cockade-like appearance with a hyporeflective center and a hyperreflective border matching the pattern observed on ICGA. At followup, as vision improved without treatment, B-scan OCT demonstrated progressive resolution of the hyperreflective and disrupted lesions; “en-face” OCT also showed disappearance of the macular cockade-like halo with a transient discrete hyperreflective macular star at the RPE level in one eye. Conclusion. “En-face” OCT associated with B-scan SD-OCT analysis appears to be very helpful in the diagnosis and followup of ARPE. The pathophysiology of ARPE remains complex and still poorly understood. These techniques help define the location and extent of structural damage occurring in this disease.http://dx.doi.org/10.1155/2013/260237
spellingShingle Flore De Bats
Benjamin Wolff
Martine Mauget-Faÿsse
Claire Scemama
Laurent Kodjikian
B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis
Case Reports in Medicine
title B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis
title_full B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis
title_fullStr B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis
title_full_unstemmed B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis
title_short B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis
title_sort b scan and en face spectral domain optical coherence tomography imaging for the diagnosis and followup of acute retinal pigment epitheliitis
url http://dx.doi.org/10.1155/2013/260237
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