Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan
Introduction: The main objective of the study was to estimate the burden of occupational tuberculosis infection in high-risk occupational workers and to identify risk factors associated with the prevalence of Mycobacterium tuberculosis complex (MTBC). Methodology: An analytical cross-sectional st...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2024-07-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/17965 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850186874753122304 |
|---|---|
| author | Chanda Jabeen Muhammad Hassan Mushtaq Jawaria Ali Khan Gulshan Umbreen Muhammad Saqib Saeed Shakera Sadiq Rubab Maqsood Hamad Bin Rashid Muhammad Asif Khalid Iqbal Sohail Ahmad Mamoona Chaudhry |
| author_facet | Chanda Jabeen Muhammad Hassan Mushtaq Jawaria Ali Khan Gulshan Umbreen Muhammad Saqib Saeed Shakera Sadiq Rubab Maqsood Hamad Bin Rashid Muhammad Asif Khalid Iqbal Sohail Ahmad Mamoona Chaudhry |
| author_sort | Chanda Jabeen |
| collection | DOAJ |
| description |
Introduction: The main objective of the study was to estimate the burden of occupational tuberculosis infection in high-risk occupational workers and to identify risk factors associated with the prevalence of Mycobacterium tuberculosis complex (MTBC).
Methodology: An analytical cross-sectional study was conducted among high-risk occupational workers including veterinarians, abattoir workers, animal handlers, livestock farmers, and microbiology laboratory workers. Sputum samples were collected from 100 participants and polymerase chain reaction (PCR) tests were done to diagnose tuberculosis (TB) infection. Data on potential risk factors was collected in a pre-designed questionnaire. The MTBC prevalence ratio was estimated. Logistic regression analysis was conducted to identify risk factors and the crude odds ratio (OR) was calculated.
Results: Among the 100 enrolled high risk occupational workers, the prevalence of MTBC was 46% (95% CI: 35.98–56.25). Living in a joint family (OR 3.85, 95% CI: 1.58–9.37), and use of unpasteurized milk (OR 3.42, 95% CI: 1.4–8.39), were significantly associated with MTBC infection.
Conclusions: Tuberculosis is a significant health burden in high-risk occupational groups, especially animal handlers and laboratory workers, in Lahore, Pakistan. The study also emphasized the need for formal work-related training, and enhanced zoonotic TB awareness among occupational workers.
|
| format | Article |
| id | doaj-art-be573235ac3d49178998a874f11f8c64 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-be573235ac3d49178998a874f11f8c642025-08-20T02:16:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802024-07-01180710.3855/jidc.17965Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, PakistanChanda Jabeen0Muhammad Hassan Mushtaq1Jawaria Ali Khan2Gulshan Umbreen3Muhammad Saqib Saeed4Shakera Sadiq5Rubab Maqsood6Hamad Bin Rashid7Muhammad Asif8Khalid Iqbal9Sohail Ahmad10Mamoona Chaudhry11Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, PakistanDepartment of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, PakistanDepartment of Veterinary Medicine, University of Veterinary and Animal Sciences, Lahore, PakistanDepartment of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, PakistanInstitute of TB and Chest Medicine, King Edward Medical University, Lahore, PakistanDepartment of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, PakistanDepartment of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, PakistanDepartment of Veterinary Surgery, University of Veterinary and Animal Sciences, Lahore, PakistanProvincial TB Control Program, Punjab, PakistanInfectious Disease Hospital, Bilal Ganj, Lahore, PakistanInfectious Disease Hospital, Bilal Ganj, Lahore, PakistanDepartment of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan Introduction: The main objective of the study was to estimate the burden of occupational tuberculosis infection in high-risk occupational workers and to identify risk factors associated with the prevalence of Mycobacterium tuberculosis complex (MTBC). Methodology: An analytical cross-sectional study was conducted among high-risk occupational workers including veterinarians, abattoir workers, animal handlers, livestock farmers, and microbiology laboratory workers. Sputum samples were collected from 100 participants and polymerase chain reaction (PCR) tests were done to diagnose tuberculosis (TB) infection. Data on potential risk factors was collected in a pre-designed questionnaire. The MTBC prevalence ratio was estimated. Logistic regression analysis was conducted to identify risk factors and the crude odds ratio (OR) was calculated. Results: Among the 100 enrolled high risk occupational workers, the prevalence of MTBC was 46% (95% CI: 35.98–56.25). Living in a joint family (OR 3.85, 95% CI: 1.58–9.37), and use of unpasteurized milk (OR 3.42, 95% CI: 1.4–8.39), were significantly associated with MTBC infection. Conclusions: Tuberculosis is a significant health burden in high-risk occupational groups, especially animal handlers and laboratory workers, in Lahore, Pakistan. The study also emphasized the need for formal work-related training, and enhanced zoonotic TB awareness among occupational workers. https://jidc.org/index.php/journal/article/view/17965MTBCoccupational workersPakistantuberculosiszoonosis |
| spellingShingle | Chanda Jabeen Muhammad Hassan Mushtaq Jawaria Ali Khan Gulshan Umbreen Muhammad Saqib Saeed Shakera Sadiq Rubab Maqsood Hamad Bin Rashid Muhammad Asif Khalid Iqbal Sohail Ahmad Mamoona Chaudhry Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan Journal of Infection in Developing Countries MTBC occupational workers Pakistan tuberculosis zoonosis |
| title | Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan |
| title_full | Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan |
| title_fullStr | Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan |
| title_full_unstemmed | Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan |
| title_short | Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan |
| title_sort | burden and factors associated with occupational tuberculosis infection among high risk workers in lahore district pakistan |
| topic | MTBC occupational workers Pakistan tuberculosis zoonosis |
| url | https://jidc.org/index.php/journal/article/view/17965 |
| work_keys_str_mv | AT chandajabeen burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT muhammadhassanmushtaq burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT jawariaalikhan burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT gulshanumbreen burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT muhammadsaqibsaeed burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT shakerasadiq burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT rubabmaqsood burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT hamadbinrashid burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT muhammadasif burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT khalidiqbal burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT sohailahmad burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan AT mamoonachaudhry burdenandfactorsassociatedwithoccupationaltuberculosisinfectionamonghighriskworkersinlahoredistrictpakistan |