Application of Spatial Omics in the Cardiovascular System
Cardiovascular diseases constitute a marked threat to global health, and the emergence of spatial omics technologies has revolutionized cardiovascular research. This review explores the application of spatial omics, including spatial transcriptomics, spatial proteomics, spatial metabolomics, spatial...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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American Association for the Advancement of Science (AAAS)
2025-01-01
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| Series: | Research |
| Online Access: | https://spj.science.org/doi/10.34133/research.0628 |
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| _version_ | 1849718577188306944 |
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| author | Yuhong Hu Hao Jia Hao Cui Jiangping Song |
| author_facet | Yuhong Hu Hao Jia Hao Cui Jiangping Song |
| author_sort | Yuhong Hu |
| collection | DOAJ |
| description | Cardiovascular diseases constitute a marked threat to global health, and the emergence of spatial omics technologies has revolutionized cardiovascular research. This review explores the application of spatial omics, including spatial transcriptomics, spatial proteomics, spatial metabolomics, spatial genomics, and spatial epigenomics, providing more insight into the molecular and cellular foundations of cardiovascular disease and highlighting the critical contributions of spatial omics to cardiovascular science, and discusses future prospects, including technological advancements, integration of multi-omics, and clinical applications. These developments should contribute to the understanding of cardiovascular diseases and guide the progress of precision medicine, targeted therapies, and personalized treatments. |
| format | Article |
| id | doaj-art-be571407f68c40bfb0addcc6dba27e88 |
| institution | DOAJ |
| issn | 2639-5274 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | American Association for the Advancement of Science (AAAS) |
| record_format | Article |
| series | Research |
| spelling | doaj-art-be571407f68c40bfb0addcc6dba27e882025-08-20T03:12:20ZengAmerican Association for the Advancement of Science (AAAS)Research2639-52742025-01-01810.34133/research.0628Application of Spatial Omics in the Cardiovascular SystemYuhong Hu0Hao Jia1Hao Cui2Jiangping Song3Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.Cardiovascular diseases constitute a marked threat to global health, and the emergence of spatial omics technologies has revolutionized cardiovascular research. This review explores the application of spatial omics, including spatial transcriptomics, spatial proteomics, spatial metabolomics, spatial genomics, and spatial epigenomics, providing more insight into the molecular and cellular foundations of cardiovascular disease and highlighting the critical contributions of spatial omics to cardiovascular science, and discusses future prospects, including technological advancements, integration of multi-omics, and clinical applications. These developments should contribute to the understanding of cardiovascular diseases and guide the progress of precision medicine, targeted therapies, and personalized treatments.https://spj.science.org/doi/10.34133/research.0628 |
| spellingShingle | Yuhong Hu Hao Jia Hao Cui Jiangping Song Application of Spatial Omics in the Cardiovascular System Research |
| title | Application of Spatial Omics in the Cardiovascular System |
| title_full | Application of Spatial Omics in the Cardiovascular System |
| title_fullStr | Application of Spatial Omics in the Cardiovascular System |
| title_full_unstemmed | Application of Spatial Omics in the Cardiovascular System |
| title_short | Application of Spatial Omics in the Cardiovascular System |
| title_sort | application of spatial omics in the cardiovascular system |
| url | https://spj.science.org/doi/10.34133/research.0628 |
| work_keys_str_mv | AT yuhonghu applicationofspatialomicsinthecardiovascularsystem AT haojia applicationofspatialomicsinthecardiovascularsystem AT haocui applicationofspatialomicsinthecardiovascularsystem AT jiangpingsong applicationofspatialomicsinthecardiovascularsystem |