Malignant perforation of sigmoid colon in long-standing ulcerative colitis

Chronic ulcerative colitis (UC) is a risk factor for malignancy in longterm disease process. Obstruction, perforation, and hemorrhage are the possible emergency situations in colorectal malignancy. A 68-year-old male with chronic UC for 18 years with steroiddependent disease (on 10 mg prednisolone d...

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Main Authors: G K Adithya, Varun Madaan, Rigved Gupta, Satya Prakash Jindal, Deepak Govil
Format: Article
Language:English
Published: SAGE Publishing 2019-01-01
Series:Apollo Medicine
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Online Access:http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=3;spage=187;epage=190;aulast=Adithya
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author G K Adithya
Varun Madaan
Rigved Gupta
Satya Prakash Jindal
Deepak Govil
author_facet G K Adithya
Varun Madaan
Rigved Gupta
Satya Prakash Jindal
Deepak Govil
author_sort G K Adithya
collection DOAJ
description Chronic ulcerative colitis (UC) is a risk factor for malignancy in longterm disease process. Obstruction, perforation, and hemorrhage are the possible emergency situations in colorectal malignancy. A 68-year-old male with chronic UC for 18 years with steroiddependent disease (on 10 mg prednisolone daily) presented with acute pain abdomen with distention not passing stool or flatus for 2 days. Diagnosed to have perforated sigmoid malignancy, underwent Hartmann's procedure. Following the adjuvant therapy, the patient denied any definitive surgery and opted to stay on Colorectal Cancer Surveillance Programme. At present, patient's positron emission tomography/computed tomography shows pelvic, liver surface, and small bowel deposits, suggestive of recurrence or metastasis. This case report is discussed to emphasis the importance of aggressive surgical treatment in longterm steroiddependent disease and poor prognosis of perforated malignancy irrespective of pathological staging.
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spelling doaj-art-be3af2cb2ae34e5daa5f39927926cf582025-08-20T01:47:40ZengSAGE PublishingApollo Medicine0976-00162213-36822019-01-0116318719010.4103/am.am_33_19Malignant perforation of sigmoid colon in long-standing ulcerative colitisG K AdithyaVarun MadaanRigved GuptaSatya Prakash JindalDeepak GovilChronic ulcerative colitis (UC) is a risk factor for malignancy in longterm disease process. Obstruction, perforation, and hemorrhage are the possible emergency situations in colorectal malignancy. A 68-year-old male with chronic UC for 18 years with steroiddependent disease (on 10 mg prednisolone daily) presented with acute pain abdomen with distention not passing stool or flatus for 2 days. Diagnosed to have perforated sigmoid malignancy, underwent Hartmann's procedure. Following the adjuvant therapy, the patient denied any definitive surgery and opted to stay on Colorectal Cancer Surveillance Programme. At present, patient's positron emission tomography/computed tomography shows pelvic, liver surface, and small bowel deposits, suggestive of recurrence or metastasis. This case report is discussed to emphasis the importance of aggressive surgical treatment in longterm steroiddependent disease and poor prognosis of perforated malignancy irrespective of pathological staging.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=3;spage=187;epage=190;aulast=Adithyachronic ulcerative colitisperforated colonic malignancysteroid-dependent ulcerative colitis
spellingShingle G K Adithya
Varun Madaan
Rigved Gupta
Satya Prakash Jindal
Deepak Govil
Malignant perforation of sigmoid colon in long-standing ulcerative colitis
Apollo Medicine
chronic ulcerative colitis
perforated colonic malignancy
steroid-dependent ulcerative colitis
title Malignant perforation of sigmoid colon in long-standing ulcerative colitis
title_full Malignant perforation of sigmoid colon in long-standing ulcerative colitis
title_fullStr Malignant perforation of sigmoid colon in long-standing ulcerative colitis
title_full_unstemmed Malignant perforation of sigmoid colon in long-standing ulcerative colitis
title_short Malignant perforation of sigmoid colon in long-standing ulcerative colitis
title_sort malignant perforation of sigmoid colon in long standing ulcerative colitis
topic chronic ulcerative colitis
perforated colonic malignancy
steroid-dependent ulcerative colitis
url http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=3;spage=187;epage=190;aulast=Adithya
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AT varunmadaan malignantperforationofsigmoidcoloninlongstandingulcerativecolitis
AT rigvedgupta malignantperforationofsigmoidcoloninlongstandingulcerativecolitis
AT satyaprakashjindal malignantperforationofsigmoidcoloninlongstandingulcerativecolitis
AT deepakgovil malignantperforationofsigmoidcoloninlongstandingulcerativecolitis