Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering

Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering

Osteoarthritis is a leading cause of disability worldwide, challenging current treatments to limited cartilage self-healing capacity. Cartilage tissue engineering (CTE) integrates cells, scaffolds, and signaling molecules, with Insulin being utilized as a differentiation biomolecule due to cost-effe...

Full description

Saved in:

Bibliographic Details
Main Authors:	Afsaneh Jahani, Mohammad Sadegh Nourbakhsh, Ali Moradi, Marzieh Mohammadi, Lobat Tayebi
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	Carbohydrate Polymer Technologies and Applications
Subjects:	Insulin 3D-printed scaffold Alginate Chitosan Cartilage tissue engineering
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666893925000350
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

EVALUATION OF POLYMORPHONUCLEAR IMMUNE CELLS IN BIOCOMPATIBILITY TEST DFLP SPONGE CARTILAGE SCAFFOLD, ADIPOSE-DERIVED MSC AND SECRETOME WITH CARTILAGE INJECTION MODEL
by: Brilliant Citra Wirashada, et al.
Published: (2020-04-01)

THE EFFECT OF DECELLULARIZATION TECHNIQUE ON COLLAGEN TYPE II AND MATRICES POROSITY OF CARTILAGE BOVINE SCAFFOLD
by: Dwikora Novembri Utomo, et al.
Published: (2019-12-01)

Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration
by: Chun-Sheng Li, et al.
Published: (2025-02-01)

SARS-CoV-2 Oral Vaccine Design Based on Nanoparticle Encapsulation with a Combination of Chitosan and Alginate
by: Ni Putu Fiona Cista Dewi, et al.
Published: (2024-12-01)

Smart Zinc-Based Coatings with Chitosan–Alginate Nanocontainers Loaded with ZnO and Caffeine for Corrosion Protection of Mild Steel
by: Kamelia Kamburova, et al.
Published: (2025-01-01)

Hydroxyapatite Chitosan Gradient Pore Scaffold Activates Oxidative Phosphorylation Pathway to Induce Bone Formation
by: Zeliang Zhang, et al.
Published: (2025-01-01)

Optimizations of Placenta Extracellular Matrix‐Loaded Silk Fibroin/Alginate 3D‐Printed Scaffolds Structurally and Functionally for Bone Tissue Engineering
by: Zahra Bashiri, et al.
Published: (2025-01-01)

Development of Alginate-Chitosan Bioactive Films Containing Essential Oils for Use in Food Packaging
by: Carla Guzmán-Pincheira, et al.
Published: (2025-01-01)

Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats
by: Jing Li, et al.
Published: (2025-01-01)

Sacrificing Alginate in Decellularized Extracellular Matrix Scaffolds for Implantable Artificial Livers
by: Chanh-Trung Nguyen, et al.
Published: (2025-01-01)

CuO-Fe2O3/calcium alginate-carboxymethylcellulose-chitosan as efficient nanocomposite beads for catalytic reduction of water pollutants
by: Nujud Maslamani, et al.
Published: (2025-01-01)

CYTOTOXIC EFFECT OF FREEZE DRIED BOVINE CARTILAGE POWDER AND PLATELET RICH PLASMA (PRP) TO MESENCHYMAL STEM CELL (MSCs)
by: Dwikora Novembri Utomo, et al.
Published: (2019-12-01)

Histology Assessment of Chitosan–Polyvinyl Alcohol Scaffolds Incorporated with CaO Nanoparticles
by: Carlos David Grande-Tovar, et al.
Published: (2025-01-01)

Investigation of biocompatibility and antibacterial properties of electrospun chitosan/ polyethylene oxide -based scaffolds containing propolis extract against Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis
by: Sayed Reza Ebrahimi, et al.
Published: (2025-02-01)

A new biocompatible delivery scaffold containing heparin and bone morphogenetic protein 2
by: Thanyaphoo Suphannee, et al.
Published: (2016-09-01)

Biocompatibility of new cement based capping material prepared from eggshell and biopolymer (chitosan).
by: Hemn M. Sarmamy, et al.
Published: (2022-07-01)

A Laryngopharyngeal Mass: Pressure Effect of the Superior Cornu of the Thyroid Cartilage Induced by a Thyroid Mass
by: Siti Farhana Abdul Razak, et al.
Published: (2024-07-01)

Chitosan Micro/Nanocapsules in Action: Linking Design, Production, and Therapeutic Application
by: Yaride Pérez-Pacheco, et al.
Published: (2025-01-01)

3D-printed constructs deliver bioactive cargos to expedite cartilage regeneration
by: Rong Jiao, et al.
Published: (2024-12-01)

Magnesium Alginate as an Electrolyte for Magnesium Batteries
by: Markus C. Kwakernaak, et al.
Published: (2025-01-01)

Pathologically altered articular cartilage attracts intense chondrocyte invasion into the extracellular matrix: in vitro pilot study
by: Victoria A. Shestakova, et al.
Published: (2024-12-01)

Progress in Research on Metal Ion Crosslinking Alginate-Based Gels
by: Yantao Wang, et al.
Published: (2024-12-01)

Effect of agarose/gelatin gel addition on the pro-angiogenic potential of polyhydroxybutyrate/chitosan scaffolds
by: Mária Giretová, et al.
Published: (2025-01-01)

Sustainable biopolymer-based spheres for controlled release of nematodes: From development to their effects under seasonal climate variations
by: Javier Pitti Caballero, et al.
Published: (2025-03-01)

Holocellulose from a Winemaking By-Product to Develop a Biopolymeric System for Bacterial Immobilization: Adsorption of Ochratoxin A in Wine Model Solutions (Box–Behnken Design)
by: Verónica Carrasco-Sánchez, et al.
Published: (2025-01-01)

Experimental investigation on the reverse mechano-electrical effect of porcine articular cartilage
by: Chunsheng Liu, et al.
Published: (2025-02-01)

Advancements in Regenerative Medicine for Articular Cartilage Repair in the Management of Osteoarthritis: A Review of Modern Treatment Methods
by: Jakub Dziewic, et al.
Published: (2025-01-01)

Recent advances in chitosan-based active and intelligent packaging films incorporated with flavonoids
by: Xuanzhuo Liu, et al.
Published: (2025-01-01)

Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis
by: Nahid Rezazadeh, et al.
Published: (2024-11-01)

Antifungal efficacy of chitosan-mediated fenugreek nanocomposite incorporated in tissue conditioner
by: Mohika Damle, et al.
Published: (2025-03-01)

Design of the Multi-Bioactive Graphene-Oxide/Gelatin/Alginate Scaffolds as Dual ECM-Mimetic and Specific Wound Healing Phase-Target Therapeutic Concept for Advanced Wound Healing
by: Marko Demenj, et al.
Published: (2025-01-01)

Cissus quadrangularis L. hexane extract infused glyoxal cross-linked chitosan-collagen scaffold elicits early osteoinduction
by: Praseetha R. Nair, et al.
Published: (2025-02-01)

Encapsulated human islets in alginate fiber maintain long-term functionality
by: Junko Nishida, et al.
Published: (2024-03-01)

A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up
by: Yao-Yi Kuo, et al.
Published: (2025-01-01)

Physicochemical Characteristics of Chitosan–Alginate Scaffold Containing Atorvastatin
by: Hananeh Hamedfar, et al.
Published: (2023-01-01)

Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+
by: Zhian Chen, et al.
Published: (2025-01-01)

Employing Polymer and Gel to Fabricate Scaffold-like Cancellous Orthopedic Screw: Polycaprolactone/Chitosan/Hydroxyapatite
by: AmirHossein Badami, et al.
Published: (2025-01-01)

Alginate Hydrogel Beads with a Leakproof Gold Shell for Ultrasound-Triggered Release
by: Marcus Flowers, et al.
Published: (2025-01-01)

Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering
by: Stefano Focaroli, et al.
Published: (2016-01-01)

Rheological Characterization and Printability of Sodium Alginate–Gelatin Hydrogel for 3D Cultures and Bioprinting
by: Mohan Kumar Dey, et al.
Published: (2025-01-01)