Histomorphological patterns of skin adnexal tumours with an insight into molecular updates - A single institutional study
Background: Skin adnexal tumors are a spectrum of benign and malignant tumors that differentiate toward or arise from the adnexal unit of the skin. These rare tumors pose a challenge in diagnosis, and often, a discrepancy is seen between clinical and histopathological diagnosis. Materials and meth...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Association of Clinical Pathologists of Nepal
2023-07-01
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| Series: | Journal of Pathology of Nepal |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/JPN/article/view/43167 |
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| Summary: | Background: Skin adnexal tumors are a spectrum of benign and malignant tumors that differentiate toward or arise from the adnexal unit of the skin. These rare tumors pose a challenge in diagnosis, and often, a discrepancy is seen between clinical and histopathological diagnosis.
Materials and methods: This single institutional study was carried out among 36 patients who presented with swelling. An initial diagnosis was considered based on the clinical history followed by histopathological examination.
Results: Among the 36 patients, only 4 had malignant tumors. Among them, 3 had sebaceous differentiation, and 1 had apocrine and eccrine differentiation. Among the benign, 14 had follicular differentiation, 12 had apocrine and eccrine differentiation, and 6 had sebaceous differentiation. The clinic-pathological correlation was 65%.
Conclusions: An accurate diagnosis is not possible with just the clinical features. Histopathologic examination is considered the gold standard for diagnosis and categorization. |
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| ISSN: | 2091-0797 2091-0908 |