A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)

Abstract The American bullfrog (Aquarana catesbeiana) is both an economically important aquaculture species and a globally distributed invasive organism with high environmental adaptability. In this study, we present a high-quality chromosome-level genome assembly for the species, comprising 13 chro...

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Main Authors: Kai Zhang, Yuxuan Zhang, Ye Tian, Bin Xu, Xiewu Jiang, Zhendong Qin, Chun Liu, Li Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04697-3
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author Kai Zhang
Yuxuan Zhang
Ye Tian
Bin Xu
Xiewu Jiang
Zhendong Qin
Chun Liu
Li Lin
author_facet Kai Zhang
Yuxuan Zhang
Ye Tian
Bin Xu
Xiewu Jiang
Zhendong Qin
Chun Liu
Li Lin
author_sort Kai Zhang
collection DOAJ
description Abstract The American bullfrog (Aquarana catesbeiana) is both an economically important aquaculture species and a globally distributed invasive organism with high environmental adaptability. In this study, we present a high-quality chromosome-level genome assembly for the species, comprising 13 chromosomes with a total length of 6.32 Gb and a scaffold N50 of 691.8 Mb. Genome completeness was evaluated at 95.5% using BUSCO and 99.9% using Merqury. Repetitive sequences accounted for 79.51% of the genome. Through a combination of RNA-seq, Ab initio and homology-based gene prediction, we identified 32,382 protein-coding genes, with 98.96% of these genes functionally annotated. This chromosome-level assembly provides an important resource for future studies on the evolution, functional genomics and molecular breeding of the American bullfrog.
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spelling doaj-art-be30723ae8014254b833742c8e7eddf02025-08-20T02:56:14ZengNature PortfolioScientific Data2052-44632025-03-011211810.1038/s41597-025-04697-3A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)Kai Zhang0Yuxuan Zhang1Ye Tian2Bin Xu3Xiewu Jiang4Zhendong Qin5Chun Liu6Li Lin7College of Animal Science and Technology, Zhongkai University of Agriculture and EngineeringCollege of Animal Science and Technology, Zhongkai University of Agriculture and EngineeringCollege of Animal Science and Technology, Zhongkai University of Agriculture and EngineeringGuangdong Hisenor Group Co.,Ltd.Guangdong Hisenor Group Co.,Ltd.College of Animal Science and Technology, Zhongkai University of Agriculture and EngineeringCollege of Animal Science and Technology, Zhongkai University of Agriculture and EngineeringCollege of Animal Science and Technology, Zhongkai University of Agriculture and EngineeringAbstract The American bullfrog (Aquarana catesbeiana) is both an economically important aquaculture species and a globally distributed invasive organism with high environmental adaptability. In this study, we present a high-quality chromosome-level genome assembly for the species, comprising 13 chromosomes with a total length of 6.32 Gb and a scaffold N50 of 691.8 Mb. Genome completeness was evaluated at 95.5% using BUSCO and 99.9% using Merqury. Repetitive sequences accounted for 79.51% of the genome. Through a combination of RNA-seq, Ab initio and homology-based gene prediction, we identified 32,382 protein-coding genes, with 98.96% of these genes functionally annotated. This chromosome-level assembly provides an important resource for future studies on the evolution, functional genomics and molecular breeding of the American bullfrog.https://doi.org/10.1038/s41597-025-04697-3
spellingShingle Kai Zhang
Yuxuan Zhang
Ye Tian
Bin Xu
Xiewu Jiang
Zhendong Qin
Chun Liu
Li Lin
A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)
Scientific Data
title A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)
title_full A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)
title_fullStr A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)
title_full_unstemmed A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)
title_short A Chromosome-level genome assembly of the American bullfrog (Aquarana catesbeiana)
title_sort chromosome level genome assembly of the american bullfrog aquarana catesbeiana
url https://doi.org/10.1038/s41597-025-04697-3
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