The application of vicasole as a perspective nephrolithyiasis pharmacological correction’s drug

The aim of the investigation was studying vicasole’s effect on experimental oxalate nephrolithiasis.Experimental nephrolithiasis was being modeled by using of 1% ethylenglycole’s solution as a drink for rats during 6 weeks. First group was control. In the second group since the third week was being...

Full description

Saved in:
Bibliographic Details
Main Authors: A. Yu. Zharikov, Ya. F. Zverev, V. V. Lampatov, V. M. Bryukhanov, O. V. Azarova, O. S. Talalayeva, Yu. G. Motin
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2012-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/401
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of the investigation was studying vicasole’s effect on experimental oxalate nephrolithiasis.Experimental nephrolithiasis was being modeled by using of 1% ethylenglycole’s solution as a drink for rats during 6 weeks. First group was control. In the second group since the third week was being administrated vicasole in dose 500 mkg/kg. Was being detected parameters of kidney’s function, markers enzymes activity and free oxygen’s radicals activity, was carried out morphological researches.It was concluded that vicasole’s therapy reduce experimental oxalate nephrolithiasis
ISSN:1682-0363
1819-3684