Advances in the study of biological agents in the treatment of Crohn’s disease

Crohn’s disease (CD) is a chronic, non-specific intestinal inflammatory disease. A large number of clinical trials have shown that biological agents are effective in inducing remission in patients with CD, and mainte-nance treatment can achieve long-term remission. At present, biological agents are...

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Main Authors: Han-Han ZHENG, Xue-Liang JIANG
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2021-12-01
Series:Yixue xinzhi zazhi
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Online Access:https://yxxz.whuznhmedj.com/storage/attach/2112/ny0owt4kQPZ1HaXCp2UAV0bENdsAtmQZ4Np82O9Y.pdf
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author Han-Han ZHENG
Xue-Liang JIANG
author_facet Han-Han ZHENG
Xue-Liang JIANG
author_sort Han-Han ZHENG
collection DOAJ
description Crohn’s disease (CD) is a chronic, non-specific intestinal inflammatory disease. A large number of clinical trials have shown that biological agents are effective in inducing remission in patients with CD, and mainte-nance treatment can achieve long-term remission. At present, biological agents are now being widely used in the treatment of CD and have become the main treatment. These include the anti-tumor necrosis factor (TNF)-α monoclo-nal antibodies, anti-integrin antibody, IL-12/23 monoclonal antibody and a Janus kinase (JAK) inhibitor. In this article, we review the progress and selection of biologics in the treatment of CD.
format Article
id doaj-art-be0dd14e778644afa9532e4470d7fea5
institution DOAJ
issn 1004-5511
language zho
publishDate 2021-12-01
publisher Editorial Office of New Medicine
record_format Article
series Yixue xinzhi zazhi
spelling doaj-art-be0dd14e778644afa9532e4470d7fea52025-08-20T02:40:39ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112021-12-0131644745410.12173/j.issn.1004-5511.2020110546267Advances in the study of biological agents in the treatment of Crohn’s diseaseHan-Han ZHENGXue-Liang JIANGCrohn’s disease (CD) is a chronic, non-specific intestinal inflammatory disease. A large number of clinical trials have shown that biological agents are effective in inducing remission in patients with CD, and mainte-nance treatment can achieve long-term remission. At present, biological agents are now being widely used in the treatment of CD and have become the main treatment. These include the anti-tumor necrosis factor (TNF)-α monoclo-nal antibodies, anti-integrin antibody, IL-12/23 monoclonal antibody and a Janus kinase (JAK) inhibitor. In this article, we review the progress and selection of biologics in the treatment of CD.https://yxxz.whuznhmedj.com/storage/attach/2112/ny0owt4kQPZ1HaXCp2UAV0bENdsAtmQZ4Np82O9Y.pdfcrohn’s disease biological agents treatment
spellingShingle Han-Han ZHENG
Xue-Liang JIANG
Advances in the study of biological agents in the treatment of Crohn’s disease
Yixue xinzhi zazhi
crohn’s disease
biological agents
treatment
title Advances in the study of biological agents in the treatment of Crohn’s disease
title_full Advances in the study of biological agents in the treatment of Crohn’s disease
title_fullStr Advances in the study of biological agents in the treatment of Crohn’s disease
title_full_unstemmed Advances in the study of biological agents in the treatment of Crohn’s disease
title_short Advances in the study of biological agents in the treatment of Crohn’s disease
title_sort advances in the study of biological agents in the treatment of crohn s disease
topic crohn’s disease
biological agents
treatment
url https://yxxz.whuznhmedj.com/storage/attach/2112/ny0owt4kQPZ1HaXCp2UAV0bENdsAtmQZ4Np82O9Y.pdf
work_keys_str_mv AT hanhanzheng advancesinthestudyofbiologicalagentsinthetreatmentofcrohnsdisease
AT xueliangjiang advancesinthestudyofbiologicalagentsinthetreatmentofcrohnsdisease