The safety and efficacy of ultrasound histotripsy and human pluripotent stem cell–derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: Assessment in an immunocompetent rodent model

The safety and efficacy of ultrasound histotripsy and human pluripotent stem cell–derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: Assessment in an immunocompetent rodent model

Liver disease secondary to an inborn or genetic error of metabolism is a rare group of conditions often associated with chronic ill health and reduced survival. Curative treatment is mainly limited to liver transplantation with major long-term risks. Cell therapy is a promising alternative, but curr...

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Bibliographic Details
Main Authors: Hassan Rashidi, Amjad Khalil, Saied Froghi, Andrew Hall, Pierre Gelat, Brian Davidson, Alberto Quaglia, Nader Saffari
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897251342462
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