Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature

Lacquer trees (<i>Toxicodendron vernicifluum</i>), economically vital, face high-temperature stress in summer. Transcriptomic, proteomic, and metabolomic analyses were employed to investigate the mechanisms by which lacquer trees respond to high temperatures. High-temperature treatment l...

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Main Authors: Guoqing Bai, Ruiwen Ding, Qizhen Su, Xiaomin Ge, Shasha Li, Huiying Shang, Aiguo Zhao, Chen Chen
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biology
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Online Access:https://www.mdpi.com/2079-7737/13/11/876
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author Guoqing Bai
Ruiwen Ding
Qizhen Su
Xiaomin Ge
Shasha Li
Huiying Shang
Aiguo Zhao
Chen Chen
author_facet Guoqing Bai
Ruiwen Ding
Qizhen Su
Xiaomin Ge
Shasha Li
Huiying Shang
Aiguo Zhao
Chen Chen
author_sort Guoqing Bai
collection DOAJ
description Lacquer trees (<i>Toxicodendron vernicifluum</i>), economically vital, face high-temperature stress in summer. Transcriptomic, proteomic, and metabolomic analyses were employed to investigate the mechanisms by which lacquer trees respond to high temperatures. High-temperature treatment led to notable metabolite changes with 224 upregulated and 69 downregulated. Indole-3-acetic acid remained stable while abscisic acid decreased, with increases in jasmonic acid and jasmonoyl-L-isoleucine indicating complex hormonal responses. JAR1 and ABA 8′-hydroxylase encoding genes were upregulated. The rise in JAs boosted the alkaloid content and activated nitrogen transport. High temperatures also increased specific amino acids and upregulated aminotransferase and protease-encoding genes. Metabolomic analysis showed elevated flavonoid glycosides and the upregulation of glycosyltransferase genes. WPCNA found 35 protein modules involved in secondary metabolite biosynthesis, protein phosphorylation, and signal transduction. Protein–protein interaction analysis revealed MYC6’s link with flavonoid biosynthesis, indicating its role in promoting flavonoids.
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institution OA Journals
issn 2079-7737
language English
publishDate 2024-10-01
publisher MDPI AG
record_format Article
series Biology
spelling doaj-art-be00664b5c094cccb005ed0d53aa0ccc2025-08-20T02:28:11ZengMDPI AGBiology2079-77372024-10-01131187610.3390/biology13110876Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High TemperatureGuoqing Bai0Ruiwen Ding1Qizhen Su2Xiaomin Ge3Shasha Li4Huiying Shang5Aiguo Zhao6Chen Chen7Shaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Xi’an 710061, ChinaEast China Academy of Inventory and Planning of NFGA, Hangzhou 310019, ChinaQinling National Botanical Garden, Xi’an 710061, ChinaShaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Xi’an 710061, ChinaShaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Xi’an 710061, ChinaShaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Xi’an 710061, ChinaCollege of Forestry, Northwest A&F University, Yangling 712100, ChinaShaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, Xi’an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Xi’an 710061, ChinaLacquer trees (<i>Toxicodendron vernicifluum</i>), economically vital, face high-temperature stress in summer. Transcriptomic, proteomic, and metabolomic analyses were employed to investigate the mechanisms by which lacquer trees respond to high temperatures. High-temperature treatment led to notable metabolite changes with 224 upregulated and 69 downregulated. Indole-3-acetic acid remained stable while abscisic acid decreased, with increases in jasmonic acid and jasmonoyl-L-isoleucine indicating complex hormonal responses. JAR1 and ABA 8′-hydroxylase encoding genes were upregulated. The rise in JAs boosted the alkaloid content and activated nitrogen transport. High temperatures also increased specific amino acids and upregulated aminotransferase and protease-encoding genes. Metabolomic analysis showed elevated flavonoid glycosides and the upregulation of glycosyltransferase genes. WPCNA found 35 protein modules involved in secondary metabolite biosynthesis, protein phosphorylation, and signal transduction. Protein–protein interaction analysis revealed MYC6’s link with flavonoid biosynthesis, indicating its role in promoting flavonoids.https://www.mdpi.com/2079-7737/13/11/876<i>Toxicodendron vernicifluum</i>high temperaturealkaloidflavonoid
spellingShingle Guoqing Bai
Ruiwen Ding
Qizhen Su
Xiaomin Ge
Shasha Li
Huiying Shang
Aiguo Zhao
Chen Chen
Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature
Biology
<i>Toxicodendron vernicifluum</i>
high temperature
alkaloid
flavonoid
title Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature
title_full Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature
title_fullStr Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature
title_full_unstemmed Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature
title_short Multiple Omics Analyses Reveal Activation of Nitrogen Metabolism and Flavonoid Glycosylation in <i>Toxicodendron vernicifluum</i> Under High Temperature
title_sort multiple omics analyses reveal activation of nitrogen metabolism and flavonoid glycosylation in i toxicodendron vernicifluum i under high temperature
topic <i>Toxicodendron vernicifluum</i>
high temperature
alkaloid
flavonoid
url https://www.mdpi.com/2079-7737/13/11/876
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