Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy

Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy

Abstract Background Ewing’s sarcoma (EwS), a common pediatric bone cancer, is associated with poor survival due to a lack of therapeutic targets for immunotherapy or targeted therapy. Therefore, more effective treatment options are urgently needed. Methods Since novel immunotherapies may address thi...

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Bibliographic Details
Main Authors: Fangzhou He, Jiuhui Xu, Fanwei Zeng, Boyang Wang, Yi Yang, Jie Xu, Xin Sun, Tingting Ren, Xiaodong Tang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cell Communication and Signaling
Subjects:
Immunotherapy
Immune modulatory
Ewing’s sarcoma
T cell
Macrophages
Online Access:https://doi.org/10.1186/s12964-024-02020-y
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