In vivo Terahertz Sensing of Skin Cancer Patients
The first in vivo study of skin cancer patients using a handheld terahertz (THz) scanner is conducted in a clinical environment. By devising a patient‐ normalized response function, it has been able to obtain clear difference between the THz measurements of healthy and cancerous skin. However, due t...
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2025-06-01
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| Series: | Advanced Photonics Research |
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| Online Access: | https://doi.org/10.1002/adpr.202400195 |
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| author | Jacob J. Young Benjamin G. Page Arturo I. Hernandez‐Serrano Joseph Hardwicke Emma Pickwell‐MacPherson |
| author_facet | Jacob J. Young Benjamin G. Page Arturo I. Hernandez‐Serrano Joseph Hardwicke Emma Pickwell‐MacPherson |
| author_sort | Jacob J. Young |
| collection | DOAJ |
| description | The first in vivo study of skin cancer patients using a handheld terahertz (THz) scanner is conducted in a clinical environment. By devising a patient‐ normalized response function, it has been able to obtain clear difference between the THz measurements of healthy and cancerous skin. However, due to the variety of lesions and skin locations measured, the contrast is not consistent between patients and more work is needed to understand the contrast mechanism. The transient behavior of the THz response is also isolated during a measurement, showing that the surface of the skin compresses during the in vivo measurement. Understanding this response has enabled the development of the patient‐invariant parameter that is formulated in this work and may potentially serve to simplify measurement protocols in future studies. |
| format | Article |
| id | doaj-art-bdfa4f240022424cbe5f9fb314bc83eb |
| institution | OA Journals |
| issn | 2699-9293 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced Photonics Research |
| spelling | doaj-art-bdfa4f240022424cbe5f9fb314bc83eb2025-08-20T02:23:48ZengWiley-VCHAdvanced Photonics Research2699-92932025-06-0166n/an/a10.1002/adpr.202400195In vivo Terahertz Sensing of Skin Cancer PatientsJacob J. Young0Benjamin G. Page1Arturo I. Hernandez‐Serrano2Joseph Hardwicke3Emma Pickwell‐MacPherson4Department of Physics University of Warwick Coventry CV4 7AL UKDepartment of Physics University of Warwick Coventry CV4 7AL UKDepartment of Physics University of Warwick Coventry CV4 7AL UKInstitute of Applied & Translational Technologies in Surgery (IATTS) University Hospital Coventry and Warwickshire Coventry CV2 2DX UKDepartment of Physics University of Warwick Coventry CV4 7AL UKThe first in vivo study of skin cancer patients using a handheld terahertz (THz) scanner is conducted in a clinical environment. By devising a patient‐ normalized response function, it has been able to obtain clear difference between the THz measurements of healthy and cancerous skin. However, due to the variety of lesions and skin locations measured, the contrast is not consistent between patients and more work is needed to understand the contrast mechanism. The transient behavior of the THz response is also isolated during a measurement, showing that the surface of the skin compresses during the in vivo measurement. Understanding this response has enabled the development of the patient‐invariant parameter that is formulated in this work and may potentially serve to simplify measurement protocols in future studies.https://doi.org/10.1002/adpr.202400195cancerin vivoterahertz |
| spellingShingle | Jacob J. Young Benjamin G. Page Arturo I. Hernandez‐Serrano Joseph Hardwicke Emma Pickwell‐MacPherson In vivo Terahertz Sensing of Skin Cancer Patients Advanced Photonics Research cancer in vivo terahertz |
| title | In vivo Terahertz Sensing of Skin Cancer Patients |
| title_full | In vivo Terahertz Sensing of Skin Cancer Patients |
| title_fullStr | In vivo Terahertz Sensing of Skin Cancer Patients |
| title_full_unstemmed | In vivo Terahertz Sensing of Skin Cancer Patients |
| title_short | In vivo Terahertz Sensing of Skin Cancer Patients |
| title_sort | in vivo terahertz sensing of skin cancer patients |
| topic | cancer in vivo terahertz |
| url | https://doi.org/10.1002/adpr.202400195 |
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