Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety
Local injection therapy (LIT) is an important component of the complex treatment of musculoskeletal disorders (MSD), which is widely used in real clinical practice. Glucocorticoids, hyaluronic acid drugs (HA), autologous cell drugs, botulinum toxin type A, radioactive isotopes, etc. are used for LI...
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2023-08-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1447 |
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| author | A. M. Lila N. V. Zagorodniy A. E. Karateev L. I. Alekseeva N. V. Chichasova G. D. Lazishvili I. F. Akhtyamov E. I. Bialik M. A. Makarov E. A. Taskina E. I. Schmidt V. V. Krylov V. E. Bialik V. A. Nesterenko |
| author_facet | A. M. Lila N. V. Zagorodniy A. E. Karateev L. I. Alekseeva N. V. Chichasova G. D. Lazishvili I. F. Akhtyamov E. I. Bialik M. A. Makarov E. A. Taskina E. I. Schmidt V. V. Krylov V. E. Bialik V. A. Nesterenko |
| author_sort | A. M. Lila |
| collection | DOAJ |
| description | Local injection therapy (LIT) is an important component of the complex treatment of musculoskeletal disorders (MSD), which is widely used in real clinical practice. Glucocorticoids, hyaluronic acid drugs (HA), autologous cell drugs, botulinum toxin type A, radioactive isotopes, etc. are used for LIT. LIT makes it possible to achieve a pronounced symptomatic effect, while in some cases, for example, repeated HA treatments in patients with osteoarthritis, the possibility of slowing the progression of the disease and reducing the need for surgical treatment is discussed.The performance of LIT requires special skills and abilities of the physician, careful compliance with the rules of asepsis and antisepsis, and instrumental visualization. LIT can be associated with serious complications and therefore must be performed according to strict indications.The Expert Council was devoted to defining the basic principles of LIT. The indications for the use of certain types of this therapies, the evidence base for its efficacy and safety, the order of application of different drugs, and the need to combine LIT with other drug and non-drug treatments of MSD were reviewed. |
| format | Article |
| id | doaj-art-bdf286f49d8d4b7d837338dd8530b08a |
| institution | Kabale University |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2023-08-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-bdf286f49d8d4b7d837338dd8530b08a2025-08-20T03:59:54ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2023-08-0117412013710.14412/1996-7012-2023-4-120-1372594Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safetyA. M. Lila0N. V. Zagorodniy1A. E. Karateev2L. I. Alekseeva3N. V. Chichasova4G. D. Lazishvili5I. F. Akhtyamov6E. I. Bialik7M. A. Makarov8E. A. Taskina9E. I. Schmidt10V. V. Krylov11V. E. Bialik12V. A. Nesterenko13V.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaN.N. Priorov National Medical Research Center of Traumatology and OrthopedicsV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaPirogov Russian National Research Medical University, Ministry of Health of RussiaRepublican Clinical Hospital of the Ministry of Health of the Republic of TatarstanV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyN.I. Pirogov City Clinical Hospital №1 of Moscow City Health DepartmentA.F. Tsyba Medical Radiological Research Center, branch of National Medical Research Center for Radiology, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyLocal injection therapy (LIT) is an important component of the complex treatment of musculoskeletal disorders (MSD), which is widely used in real clinical practice. Glucocorticoids, hyaluronic acid drugs (HA), autologous cell drugs, botulinum toxin type A, radioactive isotopes, etc. are used for LIT. LIT makes it possible to achieve a pronounced symptomatic effect, while in some cases, for example, repeated HA treatments in patients with osteoarthritis, the possibility of slowing the progression of the disease and reducing the need for surgical treatment is discussed.The performance of LIT requires special skills and abilities of the physician, careful compliance with the rules of asepsis and antisepsis, and instrumental visualization. LIT can be associated with serious complications and therefore must be performed according to strict indications.The Expert Council was devoted to defining the basic principles of LIT. The indications for the use of certain types of this therapies, the evidence base for its efficacy and safety, the order of application of different drugs, and the need to combine LIT with other drug and non-drug treatments of MSD were reviewed.https://mrj.ima-press.net/mrj/article/view/1447local injection therapyrheumatic diseasesglucocorticoidshyaluronic acidplatelet-rich plasmabotulinum toxin type aradiosynovectomy |
| spellingShingle | A. M. Lila N. V. Zagorodniy A. E. Karateev L. I. Alekseeva N. V. Chichasova G. D. Lazishvili I. F. Akhtyamov E. I. Bialik M. A. Makarov E. A. Taskina E. I. Schmidt V. V. Krylov V. E. Bialik V. A. Nesterenko Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety Современная ревматология local injection therapy rheumatic diseases glucocorticoids hyaluronic acid platelet-rich plasma botulinum toxin type a radiosynovectomy |
| title | Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety |
| title_full | Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety |
| title_fullStr | Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety |
| title_full_unstemmed | Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety |
| title_short | Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety |
| title_sort | local injection therapy in the complex treatment of musculoskeletal disorders principles of application evidence base safety |
| topic | local injection therapy rheumatic diseases glucocorticoids hyaluronic acid platelet-rich plasma botulinum toxin type a radiosynovectomy |
| url | https://mrj.ima-press.net/mrj/article/view/1447 |
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