PITX1 as a grading, prognostic and tumor-infiltrating immune cells marker for chondrosarcoma: a public database-based immunoassay and tissue sample analysis

PITX1 as a grading, prognostic and tumor-infiltrating immune cells marker for chondrosarcoma: a public database-based immunoassay and tissue sample analysis

BackgroundChondrosarcoma (CHS) is a rare bone cancer originating from chondrocytes, with high-grade cases associated with high mortality rates. However, the prognostic factors and therapeutic targets for CHS have not been studied.MethodsGraded gene differential analysis was conducted on 97 CHS tissu...

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Bibliographic Details
Main Authors: Zikun Huang, Dongchen Liu, Ying Zhang, Weiqing Lu, Lan Hu, Jinghao Zhang, Lei Xie, Shubiao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
tumor grade
PITX1
chondrosarcoma (CHS)
tumor-infiltrating immune cell (TIC)
immune targets
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1477649/full
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