Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study
Background. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/643589 |
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| author | Oscar H. Del Brutto Mark J. Sedler Robertino M. Mera Pablo R. Castillo Elizabeth H. Cusick Jadry A. Gruen Kelsie J. Phelan Victor J. Del Brutto Mauricio Zambrano David L. Brown |
| author_facet | Oscar H. Del Brutto Mark J. Sedler Robertino M. Mera Pablo R. Castillo Elizabeth H. Cusick Jadry A. Gruen Kelsie J. Phelan Victor J. Del Brutto Mauricio Zambrano David L. Brown |
| author_sort | Oscar H. Del Brutto |
| collection | DOAJ |
| description | Background. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure ≥65 mmHg were suspected of asymptomatic PAD. In Phase II, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In Phase III, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. Results. During Phase I, 665 Atahualpa residents aged ≥40 years were enrolled (mean age: 59.5 ± 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. Conclusions. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region. |
| format | Article |
| id | doaj-art-bde57c9fbd254128b59486336ed0e652 |
| institution | Kabale University |
| issn | 2090-2824 2090-2832 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Vascular Medicine |
| spelling | doaj-art-bde57c9fbd254128b59486336ed0e6522025-02-03T05:52:47ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322014-01-01201410.1155/2014/643589643589Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary StudyOscar H. Del Brutto0Mark J. Sedler1Robertino M. Mera2Pablo R. Castillo3Elizabeth H. Cusick4Jadry A. Gruen5Kelsie J. Phelan6Victor J. Del Brutto7Mauricio Zambrano8David L. Brown9School of Medicine, Universidad Espíritu Santo-Ecuador, Guayaquil, EcuadorSchool of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USAGastroenterology Department, Vanderbilt University, Nashville, TN, USASleep Disorders Center, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USASchool of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USASchool of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USASchool of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USACommunity Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, EcuadorCommunity Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, EcuadorCardiovascular Division, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8086, St. Louis, MO 63110, USABackground. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure ≥65 mmHg were suspected of asymptomatic PAD. In Phase II, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In Phase III, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. Results. During Phase I, 665 Atahualpa residents aged ≥40 years were enrolled (mean age: 59.5 ± 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. Conclusions. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region.http://dx.doi.org/10.1155/2014/643589 |
| spellingShingle | Oscar H. Del Brutto Mark J. Sedler Robertino M. Mera Pablo R. Castillo Elizabeth H. Cusick Jadry A. Gruen Kelsie J. Phelan Victor J. Del Brutto Mauricio Zambrano David L. Brown Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study International Journal of Vascular Medicine |
| title | Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study |
| title_full | Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study |
| title_fullStr | Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study |
| title_full_unstemmed | Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study |
| title_short | Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study |
| title_sort | prevalence correlates and prognosis of peripheral artery disease in rural ecuador rationale protocol and phase i results of a population based survey an atahualpa project ancillary study |
| url | http://dx.doi.org/10.1155/2014/643589 |
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