Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats

Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats

Objective. To investigate the role of microRNA-130b in 1,25(OH)2D3 mediated improvement of renal fibrosis via transforming growth factor-beta 1 in a rat model of diabetic nephropathy (DN). Methods. DN was induced in 30 rats by intraperitoneal injection of streptozotocin. These rats were randomly all...

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Bibliographic Details
Main Authors:	Yuetong Liu, Ye Yang, Qin Wang, Apaer Kahaer, Jiyun Zhang, Jing Liao, Mairemugu Abudureyimu, Reyila Yahefu, Jing Qi, Lei Zhao, Jun Zhu
Format:	Article
Language:	English
Published:	Wiley 2019-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2019/1231346
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