Heterochronic pelvic high-grade myxoinflammatory fibroblastic sarcoma and uterine endometroid carcinoma harboring common gene mutations: a rare case report with genomic analysis

Heterochronic pelvic high-grade myxoinflammatory fibroblastic sarcoma and uterine endometroid carcinoma harboring common gene mutations: a rare case report with genomic analysis

Abstract Objective This report presents a rare case involving an extreme epithelial-to-mesenchymal transition, in which a specific type of sarcoma developed heterochronically as a recurrence of endometrioid carcinoma. Case presentation A female in her 50’s presented with abnormal genital bleeding, a...

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Bibliographic Details
Main Authors: Yuriko Higashi, Mika Mizuno, Ikumi Kitazono, Toshiaki Akahane, Takashi Tasaki, Hirotsugu Noguchi, Masanori Hisaoka, Hiroaki Kobayashi, Akihide Tanimoto
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Diagnostic Pathology
Subjects:
Endometrioid carcinoma
Pelvic sarcoma
Myxoinflammatory fibroblastic sarcoma
Next-generation sequencing
Gene mutations
Epithelial-to-mesenchymal transition
Online Access:https://doi.org/10.1186/s13000-025-01669-4
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